Vol 4 Issue 2 October 2016-March 2017

Abstract: Total laryngectomy is the procedure in which the throat is completely eliminated as well as the air passage is interrupted, respiration being executed via a tracheal stoma arising from bringing the trachea to the skin in the reduced, former, cervical location. We aimed by this article to overview the Total laryngectomy from several aspects, and mostly to imprecise the surgical techniques, the complications and, the post-surgical outcomes. We have undertaken an extensive review of the literature using several medical databases; MIDLINE, and EMBASE are the most that we conducted our study through, searched involved studies from time of instance up to the 2017. We identified studies only which published in English language and with human subjects. This review was concerned to these studies involving the discussion of any aspect of Total laryngectomy. Patients with cancer of the throat had a substantially much better survival complying with complete laryngectomy compared to patients with partial larnyectomy. The growth of efficient methods for decreasing and/ or avoiding such respiratory system issues would contribute dramatically to enhancing the lifestyle of laryngectomized patients. New medical methods and also voice prostheses have raised the populace of patient’s ideal for TE voice reconstruction. This has a positive effect on the lifestyle for patients going through total laryngectomy. Keywords: Total laryngectomy, Tracheal Stoma Arising. Title: Total Laryngectomy, Consequences and Outcomes: An Overview Author: Thamer Saad Shaker Alghalbi, Ghalib Nasser Aldawsari, Anwar Saeed Alghamdi, Abdullah Saeed Alghamdi, Fahad Awadh Almalki, Badr Abubaker Babatin International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Present study goal was to review the evidence about pathogenesis, diagnosis, and treatment approaches for Addison disease or as its also called primary adrenal insufficiency. PubMed, Medline, and Embase databases were comprehensively searched for relevant articles reporting Addison disease treatment options, pathogenesis and other different clinical aspects concerning this disease, with human subjects and only articles published in English language up to December, 2016. The cutaneous manifestations include darkening of the skin especially in sun-exposed areas and hyperpigmentation of the palmar creases, frictional surfaces, vermilion boundary, current marks, genital skin, as well as oral mucosa. The 250 μg ACTH stimulation examination supplies the medical diagnosis of adrenal insufficiency in the majority of patients. Dimension of totally free lotion or salivary cortisol could be useful when CBG is reduced, yet calls for standardization. Adrenal deficiency is connected with lowered lifestyle that may be caused by non-physiological glucocorticoid substitute. Keywords: pathogenesis, diagnosis, treatment, frictional surfaces, vermilion boundary, genital skin. Title: Overview of Pathogenesis and Treatment Options of Addison Disease Author: Abdulrahman Hussain Haddad, SAWSAN MOHAMMED ABU HADI, Abeer Abdalaziz Alhatem, Abdulrahman Saad Albakheet, Saad munawwikh alshammari, Salman jubran farhan almalki, Sultan jubran farhan almalki, Fatima Ali Albinalshikh, Sultan jaber m alfaifi, Muataz Ibrahim Alnami, AL MARAIH IBRAHEEM FARA M, ABDULLAH YAHYA AL JAMAHIR, Abdulrahman A bubakr Sharwani International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: This review was aimed to discuss and overview the Acute erythroid leukemia (AEL) from different clinical aspects, diagnosis, prognosis, and treatment approaches, using evidence based trails to support our study discussion. We conducted a comprehensive electronic search through medical databases; PubMed, Medline and Emabse, for studies concerned with the Acute erythroid leukemia (AEL) from any aspects, and published up to January 2017, with human subjects only and with restriction to English language articles. Furthermore, references lists of found articles were reviewed for more relevant studies. AEL is an unusual group of heterogeneous diseases with several neoplastic as well as non-neoplastic problems simulating the medical diagnosis. The medical discussion and also cytogenetics are likewise non-specific offering added difficulties to the medical diagnosis. It has an inherent biological connection with MDSs, it has an even worse professional actions. Among the thoughts of phasing out this diagnosis as well as combining it with MDS, one need to value its differences in medical outcomes. A probable age change when it come to a more youthful populace calls for even more studies here. Keywords: Acute erythroid leukemia (AEL), Professional Actions. Title: Overview of Acute Erythroid Leukemia (AEL), Diagnosis, Prognosis, and Current Treatment Author: Abdulwahab Hussain H. Alawaji, Mohammed Saeed Alshahrani, Qasem Abdu Mahzari, Faisal Mohammed Al-atawi, Hisham Hussain Alawaji, Jamal Ali Albalawi, Turki Saleh Alshehri, Abdulaziz Ibraheem S. Alhowidi, Darin Abdusalam Fallatah, Alaa Eid Al Johani, Ali Haussain Alfahal, Hasan Salman Alkhlaf, Ahmed Abdulaziz Almuhamdi, Waheed Ali Alshehri, Hussain Ali Khubrani International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: The objective of this comprehensive review study was to focus on the different surgical intervention for treatment of different types of hepatic cysts. Also to discuss the different types of cysts and most common types. We comprehensively searched PubMed, EMBASE, and the Cochrane Library for studies involving humans surgically treated for any type of hepatic cyst, and published in English up to November 2016. Every references of chosen article were screened for more relevant studies which can be useful for our review. When laparoscopic surgical procedure, both traditional and also radical, is performed for hepatic cysts, there should be no concession in the concept of staying clear of cyst material spilling as well as maintaining the integrity of the cyst wall. The reported reappearance price for open surgery arrays from 0% to 4.5% in different studies, however the reported collective recurrence rate is 1.1% for the laparoscopic therapy of liver cysts. Indicating the safety of these procedures in selected patients. The advantages for patients consist of excellent cosmetic results and also a much shorter health center keep. It shows up that the price is lower complying with radical procedures as a result of much better control of the recurring cavity as well as neighborhood reoccurrence. However, the radical approach is normally reserved for peripherally located cysts; if taken care of incorrectly, this strategy may create major bleeding and hence conversion. Keywords: surgical intervention, types of hepatic cysts. Title: Surgical Treatment Approaches of Hepatic Cysts: A Review Author: Ali Khalid Alkhaldi, Khalaf Safar Saeed Alghamdi, Ahmed Essa Abdulaziz Alkhaldi, Abdulrahman Nasser Abdulrahman Alfayyadh, Mohammed Ahmed Abdulrahman Alfayyadh International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: The present study describes and overview the procedures of a minimally invasive technique of facial skin rejuvenation, as a reconstructive cosmetic intervention, also aimed to evaluate the different techniques used in facial rejuvenation. We Conducted a comprehensive computerized review of literature reporting minimal invasive technique of facial rejuvenation published in English language until January,2017 this search was performed using electronic databases; PubMed, Medline, and Embase. Choosing the ideal therapy method which will certainly be the secret to success in skin restoration depends upon cautious evaluation as well as figuring out the patient's requirements, skin kind and problem, to mount a therapy strategy. Excellent prospects for minimally invasive methods have the tendency to have minimal face sagging. Patients must understand that skin appearance will improve and great lines will certainly be softened but not eliminated. Cumulative aesthetic benefits will certainly occur slowly and will certainly be less dramatic than those seen with ablative resurfacing. Keywords: facial skin rejuvenation, minimal invasive technique, patient's. Title: Minimally Invasive Facial Rejuvenation: Review Author: Abdullah Ayed Al_Nefaie, Abdullah Khalid Alsuwat International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Helicobacter pylori, is a gram-negative, spiral bacterium located on the epithelial surface area of the stomach. The main Goal of our study was to overview the management approaches toward Helicobacter pylori infection, and also to discuss the complications occurring during this bacterial infection, such as antibiotics resistance. Medline, PubMed and Embase databases were searched for treatment options and approaches of Helicobacter pylori for the period until January 2017. Several studies have shown that the updates on the management procedures of H. pylori, and different guidelines were reviewed for more evidence about the steps on treatment of H. pylori infection. Including 2 antibiotics and a proton-pump inhibitor proposed as the first-line program. Probiotics treatment, are an alternative therapy that discovered to be extremely usefull treatment line of H. pylori infection. Levofloxacin containing triple treatment are recommended as rescue treatment for infection of H. pylori after defeat of first-line treatment. The rapid acquisition of antibiotic resistance minimizes the effectiveness of any regimens involving these remedies. Therefore, adding probiotic to the medications, developing anti-H. pylori phytomedicine or photodynamic therapy, and accomplishing a successful H. pylori vaccine might have the appealing to present synergistic or additive consequence against H. pylori, since each of them apply different results. Keywords: Helicobacter Pylori, Epithelial Surface Area, Bacterial Infection. Title: A Review of Treatment Approaches of Helicobacter Pylori Infection and its Complications Author: Najlaa Samran Almutairi, Amani Hamed Hassan Suqi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Scorpion sting is a common medical problem worldwide speasialy in Saudi Arabia, because of the geographical distribution that combines deserts and mountains which is favorable for deferent types of scorpions. It is important to know that scorpion stings had a wide range of presentation started from redness and pain till life threatening conditions. We present a 20 years old male patient who had a scorpion sting and he presented with benign fibrous histiocytoma which is a rare presentation, followed by discussion on the case. Keywords: Scorpion sting, histiocytoma. Title: Scorpion Sting Leads to Histocytoma: Case Report Author: Adel Alhabash, Ahmad Almaghrabi, Abdulrahman Alzamzami, Muath Damanhuri, Yousif Howsawy International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Evidence on treatment of Pyoderma gangrenosum (PG) were reviewed aiming to describe the proper management option for PG, also in this review intended to discuss the diagnosis, and pathophysiology of PG, to have great understanding for present concerned dermatological disease. PubMed, Embase databases were searched for relevant articles, related to the Pyoderma gangrenosum (PG), wether concerned with treatment challangest or diagnostic approach or even clinical features of PG, which are published before the end of 2016, and contained only human subjects. No language restriction was applied in this search. Pyoderma gangrenosum is a serious however uncommon ulcerating skin disease, the treatment of which is mainly empirical. Pyoderma can provide to a range of health specialists and a number of versions exist that may not be recognised immediately. The finest recorded treatments are systemic corticosteroids and ciclosporin A. Combinations of steroids with cytotoxic drugs are used in resistant cases. The combination of steroids with sulfa drugs or immunosuppressants has been utilized as steroid-sparing methods. Anti-tumor necrosis alpha treatment in Crohn's disease showed a fast response of PG. Keywords: Pyoderma gangrenosum (PG), dermatological disease, treatment, human subjects. Title: Pyoderma Gangrenosum,Treatment Challenges Author: Mohammed Ahmed M Alabyad, FAWAZ TARIQ H ALSAMDANI, Abdullah Ahmed A Alghamdi, Khalid mohamad gormallh al-ghamdi, Awatef Ayed M Alshammari, FAEZ MOHAMMADHASAN ZAGZOUG International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: This review was aimed to Overview the topical treatments for psoriasis, as well as the evidence and rationale for combining therapies of these topical treatments. Also intended to discuss the efficiency and adverse effect of various mentioned topical therapies. We conducted a comprehensive literature searches via PubMed and Embase databases, searching relevant studies concerning with topical therapies for psoriasis published in English up to December 2016. Our search was performed using the search term “psoriasis” combined with “topical treatment.” Furthermore, we searched references lists of those chosen articles for more relevant studies to be included in present review. Only studies with human subjects were included in this review Topical When utilized properly as well as has the benefit of limited systemic effects, therapy is effective and also secure. When suggesting a topical therapy one has to consider a number of factors, including patient inspiration as well as understanding, lorry of medicament, quantity of treatment called for and require for dressings. Topical treatment could be greasy, bothersome, difficult as well as time-consuming for patient. When topical therapies fall short, improving adherence to topical treatments is vital to promote better clinical result; clinicians should constantly take into consideration non-adherence. Topical therapy of psoriasis has actually evolved from the age-old applications of tar and also dithranol to the extra efficacious and also appropriate choices of topical corticosteroids, and also vitamin D analogues. Keywords: Topical Treatments for Psoriasis, Greasy, Bothersome. Title: An Overview of Topical Treatment of Psoriasis, Variation and Adverse Effects Author: Amani Ali Madkhali, Nehad Khalaf Khawaji, Amany Ibraheem Mashi, Aisha Yahya Alkhaldy, Tahani Ahmed Moafa, Abdulrhman Jaber Hakami, Zainab Ahmad Jafari, Mohannad Faisal Tobaigy, Amwaj Jabir Mohanna, Ebtesam Eissa Madkhali, Abdu Mohammed Hamdi, Hatim Saeed Alessa International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Leukocytosis has actually been associated with thrombosis and death in cancer patients. We explored the association of leukocytosis with venous thromboembolism (VTE) and early death in cancer patients initiating chemotherapy. Data from a potential, multicenter observational study of treatment-related problems in 4,405 ambulatory cancer patients initiating chemotherapy was utilized for this analysis. The association of leukocytosis, VTE and mortality during the course of chemotherapy was examined in multivariate and univariate analysis. In conclusion, Elevated WBC, especially neutrophils, is highly associated with increased threat of VTE and death in cancer patients receiving systemic chemotherapy. Further studies are had to elicit the mechanisms involved. Keywords: Venous Thromboembolism (VTE), Medications, induce Leukocytosis. Title: Overview of Medication That Induce Leukocytosis Author: Mohammed Abdullah Mohammed Alkathiri, Riyadh Farraj S Al Areef, Mohanad Jebril Bosily, Saleh Ali M Alsagti, Ahmed Sultan Ahmed AlAmri, Osamah Mohammed Saad Alqahtani, Abdulrahim Moshabbab Hamhom, Asiri, Sultan Abdulwahab M International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: We aimed by this review study to discuss and overview the prevalence of Impetigo and scabies worldwide, and dermatological consequences beyond that, as well as to review the treatment options for these dermatological diseases. We searched Medical databases; MEDLINE, PubMed, and Emabse, for studies that reported on the epidemiology of scabies and impetigo, and also those studies discussing the treatment approaches of same diseases, Mesh terms as following; “scabies”, “Sarcoptes scabiei”, “impetigo”, or “dermatological disease”, combined with “incidence”, “prevalence”, “epidemiology”, “diagnosis”, or “Treatment”. Restriction was applied to only English language studies with human subjects published up to January 2017. Island nations of the Pacific were the most afflicted populations, with scabies and impetigo especially common in children. Other locations where scabies frequency was particularly high consisted of Panama, parts of Brazil, and Indigenous neighborhoods of northern Australia. Scabies and impetigo were especially common in tropical developing countries. There are safe and efficacious treatments readily available for these typical skin infections, yet in lots of locations where disease burden is highest, bit has altered with regards to control. Ongoing research checking out risk factors and aetiology, improved approaches for medical diagnosis and approaches to both private and neighborhood based treatment is needed. Keywords: Impetigo, scabies, Sarcoptes scabiei, dermatological disease, incidence, Treatment. Title: Overview of Epidemiology and Treatment Impetigo & Scabies Author: FATEN SAUD M ALJEHANI, Mohammed Ayed M Alshammari, Mohammed Ahmed M Alabyad, Arwa talal d algaidi, FAWAZ TARIQ H ALSAMDANI, Abdullah Ahmed A Alghamdi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: The objective of this review was to discuss the pathogenesis of Polycystic kidney disease (PKD), as well as the diagnosis and treatments approaches, through reviewing the evidence based on this manner. Databases; PubMed, and Embase were computerized searched for relevant studies concerning the Polycystic kidney disease (PKD), published in English language until the end of 2016. more relevant articles were extracted through searching the literature included in references of selected studies. Autosomal dominant polycystic kidney disease (ADPKD) is a common, acquired condition for which there is presently no effective specific medical therapy, pathologic accumulation of fluid in epithelium lined cavities causing the damage of adjacent regular parenchyma. Acquired cystic diseases, consisting of the most prevalent form, ADPKD, kidney ultrasonography is commonly utilized for the medical diagnosis of ADPKD and age-dependent criteria have been specified for subjects at-risk of PKD1. The utility of the PKD1 ultrasound criteria in the center setting is uncertain considering that their efficiency qualities have not been specified for the milder PKD2 and the gene type for a lot of test topics is unknown. Keywords: Polycystic kidney disease (PKD), Diagnosis, treatments approaches. Title: Polycystic Kidney Disease, Pathogenesis, Diagnosis, Treatment: Review Author: Mohammed aqeel Jaafari, Mousa Mohammed Hadi, Faisal Mohammed Ali Gasmi, Ali shaya kaabi, Ahmad Mosa Ali Faqeeh, Anas Mohammed Alnahari International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: The Goal of this review was to introduction the Bariatric surgery procedures, also to evaluate which treatment, and problem which follow after these various surgeries. We conducted an electronic literature search of MEDLINE, EMBASE, and Cochrane Library databases, until December 2016.This paper briefly summarizes present surgical choices for weight loss with a focus on the majority of utilized procedures. Bariatric surgical treatment should be considered for patients who have actually not achieved adequate weight reduction with lifestyle and medical management who are at high risk of morbidity and death, and who are struggling with the complications of obesity. Success with bariatric surgery is most likely when multidisciplinary health care suppliers, in conjunction with primary health care suppliers, evaluate, treat, keep an eye on, and assess individuals both before and after surgery. Cosmetic surgeons ought to use the competence of their multidisciplinary care group to promote and manage the health of their bariatric surgical patients. Nevertheless, SG achieves clearly much better results than other limiting methods and is equivalent in some elements to the Roux-en-Y gastric bypass, the present gold requirement in bariatric surgical treatment. Keywords: Bariatric surgery procedures, various surgeries, bariatric surgery. Title: Comprehensive Review of Bariatric Surgery Procedures Author: Mohammed aqeel Jaafari, Mousa Mohammed Hadi, Faisal Mohammed Ali Gasmi, Ali shaya kaabi, Ahmad Mosa Ali Faqeeh, Anas Mohammed Alnahari International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Atopic dermatitis (AD; likewise called atopic eczema or eczema) is a chronic inflammatory, pruritic skin disease with significant quality of life (QOL) consequences for both patients and families(1-3). Affecting # 30% of children and 10% of adults(4). A wide variety of instruments targeted at measuring AD outcomes exist. Given the typically concurrent physiological and psychological concerns of AD The purpose of this study was to evaluate by organized evaluation recent trends in disease severity and QOL result instruments used in RCTs on patients with AD that were performed between July 2000 and July 2015. Specifically, we looked for to establish the following: 1) the percentage of examined studies utilizing disease seriousness or QOL outcome steps; 2) the overall number and frequency of use of disease intensity scales; and 3) the total number and frequency of QOL instruments utilized. Four databases were selected to ensure a comprehensive review of the literature: PubMed, EMBASE, Ovid, and the Cochrane Review. On January 25, 2014, a total of 9 different queries were used for each engine: (1) “Atopic dermatitis ” (2) “atopic neurodermatitis” (3) “disseminated neurodermatitis ” (4) “atopic eczema ” (5) “infantile eczema,” (6) “Children’s Dermatology Life Quality Index” (7) “Dermatitis Family Impact ” (8) “Dermatology Life Quality Index ” (9) “randomized controlled trial ”. A hand search of the tables of contents of relevant journals published from January to December 2015 was then performed. Our methodical review identified a total of 62 disease intensity scales from the 135 consisted of studies. This is an extreme increase from the 20 disease severity scales determined in Rehal and Armstrong's review(8) of 382 RCTs on AD treatment published in between 2000 and July 2015. Just like Rehal and Armstrong's findings(8) , the SCORAD index(9), stayed the most popular disease severity instrument. Keywords: Atopic dermatitis (AD), Quality Of Life (QOL). Title: Review of Scales Used To Assess the Atopic Dermatitis Severity Index and Quality Of Life Author: Shrooq Tail Alkhodaidi, Albaraa Y. Alsini International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Abstract: Musculoskeletal conditions represent among the largest reasons for years dealt with disability in high-income economies. These conditions are primarily managed in medical care settings, and yet, there is a paucity of evidence on which approaches work well in increasing the uptake of finest practice and in closing the evidence-to-practice space. Significantly, musculoskeletal models of service delivery (as components of designs of care) such as incorporated care, stratified care and therapist-led care have actually been evaluated in main health care pathways for joint pain in older adults, for low neck and back pain and for arthritis. In this chapter, we discuss why application of these designs is important for primary care and how designs are carried out using three case examples: we review application theory, outcomes and concepts; we consider the function of health financial assessment; and we propose key proof spaces in this field. We propose the following research study top priorities for this location: examining the generalizability of models of care throughout, for example, rural and city settings, and for different musculoskeletal conditions; increasing support for self-management; comprehending the importance of context in picking a model of care; detailing how implementation has been carried out; and examination of application and its impact. The main objective of this review is to establish the impact upon patients and health services, of substituting doctors with physiotherapists in the management of common musculoskeletal disorders. Keywords: Management of musculoskeletal, high-income economies. Title: Management of Musculoskeletal Disease and Exercise in Primary Care Author: Rawan Khalid Z.Alhamdan, Fajer Abdullah Ahmed Alwehaibi, Sarah Abdulalim Alzaid, Sumaia Saleh Mohammed Akazami, Hissah Saad Al Ghoraibi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals