Abstract: Background: Mallotus repandus belonging to the euphorbiaceae family is an important medicinal plant which is widely distributed in tropical and subtropical regions of Asia. Traditionally, It has been reported to show antioxidant, antiviral, antimicrobial, cytotoxicity, anti-inflammatory, anti-ulcerogenic, hepatoprotective and hypoglycemic activities in various country of the world.
Helicterus isora belonging to the sterculiaceae family is a small tree, found in Australia, Saudi Arabia, India, South China, and other parts of Asia. Demulcent, astringent, hepatoprotective, antidiabetic, expectorant, antioxidant, antibacterial etc activities have been reported to show by various parts of this plant.
The aim of this study was to detect some of the phytochemicals of both plants which could justify their use in various ailments and thus could be potential source of novel drug.
Methods: GC MS analysis of methanol extract of leaves of Mallotus repandus and Helicterus isora was performed to detect phytochemicals.
Result: GC MS analysis of MEMR detected twenty four (24) chemical compounds such as : Caryophyllene; n-Hexadecanoic; 9,12,15-Octadecatrienoic acid; methyl ester (Linolenic acid, methyl ester); 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (Phytol); Vitamin E (α-Tocopherol); 9,12,15-Octadecatrienoic acid, (Z,Z,Z)- (Linoleic acid); 13-Docosenamide etc. On the other hand, 2,4(1H,3H)-Pyrimidinedione, 5-methyl- (Thymine); Xanthine riboside 9-beta-D- Ribofuranosylxanthine (Xanthosine); cis-9-Hexadecenal; 13-Docosenamide, (13Z)- (Erucamide); α-Tocopherol (Vitamin E); Stigmasta-5,22-dien-3-ol, (3beta,22E)- etc have been detected in GC MS analysis of MEHI.
Conclusion: The identification of biologically active compounds may explain the scientific reasons for their use as traditional medicine and can open a path to formulate them as medicine.
Keywords: GC MS, MEMR, MEHI, Traditional medicine, phytochemicals.
Title: GC-MS analysis of methanol extract of leaves of Mallotus repandus and Helicterus isora
Author: Reshmi Akter, Anamul Hasan Saikat, Md. Shahed-Al-Mahmud, Anawara Begum
International Journal of Interdisciplinary Research and Innovations
ISSN 2348-1218 (print), ISSN 2348-1226 (online)
Vol. 12, Issue 2, April 2024 - June 2024
Page No: 45-54
Research Publish Journals
Website: www.researchpublish.com
Published Date: 24-June-2024