Vol 4 Issue 2 April 2016-June 2016

Abstract: The evaluation of the wood of Cordia milleni was carried out in terms of chemical, physical and variable techniques; oven dry density, water imbibitions (at different intervals: 30 mins, 5 hrs & 24 hrs), thermal conductivity, electrical conductivity, afterglow time, flame duration, flame propagation rate, ignition time, moisture content and ash content showed that it is a good timber suitable for various construction purposes. Phytochemical screening showed the presence of saponins, tannins, steroids, flavonoids, carbohydrates, proteins, resins, terpenoids, glycosides and alkaloids. The AAS of the sample showed the presence of some metals such as Na, K, Pb, As, Ca, Zn, Mg, and Cu in the decreasing order of their concentrations. The TLC analysis showed one spot for chloroform-methanol extracts and two spots for chloroform extracts. It was further characterized using Fourier Transform Infrared and Ultraviolet Spectroscopic methods which suggested a 1,2,3- trisubstituted phenylamide with OH,CO and CN groups attached as the functional groups present. The chemical components analysis showed the presence of cellulose, hemicelluloses, lignin and other constituents in their right proportion. The results confirmed the efficiency of the wood for various construction purposes and its medicinal ability due to the presence of the secondary metabolites. Keywords: Cordia milleni, Chloroform-methanol, Functional group, chemical constituents and Tropical timber. Title: An Assay of Characteristics, Chemical Constituents and Functional Group Analysis of Cordia Milleni: A Tropical Timber Author: Udeozo, I.P., Ejikeme, C.M., Eboatu, A.N., Arinze, R.U., Kelle, H.I. International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Research Publish Journals

Abstract: Ferritin is the storage form of iron and its role has been implicated in s variety of human diseases. Among the assays carried out to assess the role of iron, such as serum free iron, protein bound iron, transferrin and % saturation, the plasma content of ferritin is the most clinically useful parameter to understand its role in many diseases such as obesity, DM, anemia and diseases associated with liver, kidney, cardiac, reproductive and psychiatric disorders. This review article brings out the outcome of research done on the clinical usefulness of ferritin in the diseases outlined above. The content of this review article will be useful to undertake iron supplement as curative therapy for patients with hypo ferritinemia. Keywords: Ferritin, DM, Anemia, Obesity, Infertility, Psychiatry. Title: Clinical Usefulness of Ferritin in Health and Diseases Author: Swaminathan Selvanayagan, Rajeswari Shanmugam, Revathy Kuppusamy International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Research Publish Journals

Abstract: Autophagy is a cellular self-degradation system that transfers cytoplasmic components to the lysosome by means of autophagosome. A wide array of molecules has been linked to the formation of this structure. LC3, a structural protein of autophagosome membrane, is widely studied protein among others, due, mainly, to its participation at different stages of autophagy. For the same reason, it has been successfully used as a biomarker of autophagy. Recent progress has demonstrated LC3 cycling between nucleus and cytoplasm in an autophagic-dependent manner. In this regard, some intracellular mechanisms have also been proposed that underline nucleocytoplasmic shuttling of LC3, such as protein-protein interaction and deacetylation/ acetylation reaction. The aim of this review is to discuss the distribution of LC3 in the nucleus and cytoplasm in the light of recent findings, and highlighting pathways regulating LC3 shuttling. Keywords: Autophagy, LC3, Nucleocytoplasm, Nucleus, Cytoplasm, Dispersal. Title: Nucleocytoplasmic Dispersal of Autophagosome Marker LC3 Author: Rawaz Sulaiman International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Research Publish Journals

Abstract: Marigold (Tagetes patula) and Red orach(Atriplex hortensis var.rubra) besides being ornamental plants, have various medicinal properties—they are nematocidal,fungicidal, antibacterial and insecticidal and aids in wound healing. Extraction of active constituents was done by conventional as well as the Soxhlet method, which was found to be much more efficient using a petroleum ether (B.P 60̊) as solvent. Blood clotting activity of the leaf extract were examined using aminal models (Rabbits and Mice) invivo for both topical and systemic administration .Our work is focused on the blood clotting activity of the leaf extracts and to check the type of chemically active ingredients present in them by various phytochemical evaluation.Analytical methods like Thin Layer Chromatography and Ultraviolet Visible Spectroscopy was also performed for qualitative analysis and comparison with a standard drug. Further research is needed for identification and quantification of its bioactive compounds, which could be purified further and chemically isolated .Further improvisation on this can possibly make it a suitable medication on use with appropriate vehicle. Keywords: Tagetes patula(Marigold);Atriplex hortensis var.rubra(Red orach);blood clotting activity,Thin Layer chromatography,Ultraviolet Visible Spectroscopy. Title: Experimental Demonstration of Blood Coagulating Property of Tagetes Patula & Atriplex Hortensis Var.Rubra Author: Rajanya Roy, Sagar Singh Kang, Gautam Kumar Bagchi International Journal of Life Sciences Research ISSN 2348-313X (Print), ISSN 2348-3148 (online) Research Publish Journals