A Comparative Study- Efficacy and Safety of Intravenous Iron Sucrose & Intramuscular Iron Sorbitol in Iron Deficiency Anemia during Pregnancies in Low Socio Economic Status

Kadri Yogesh Bangera, Sujay Heranjal, Chethan K

Abstract: Most women are not able to develop adequate iron stores during growth period. Thus women enter pregnancy state with depleted iron stores. This is a prospective Randomized controlled study conducted on women in the 2nd & early 3rd trimester of pregnancy with iron deficiency anaemia The mean age group in this study is 22.9+3.7 yrs, 43.33% of them were primigravida’s & 56.7% of them were multigravida’s.  In iron Sorbitol group the mean rise in Hb% was by 0.8+0.17gm% at 4wks & 1.72+0.5gm% at delivery. Mean reticulocyte count by 0.46+0.14% & mean hematocrit rise was by 3.5+2.3% at 4wks & by 4.1+2.2% at delivery. In iron Sucrose group the rise in mean Hb% was by 2.2+0.4gm% at 4wks & by 3.04+0.5 gm% at delivery.  Mean reticulocyte count by 0.46+0.15% & increase in mean hematocrit was 6.2+2.2% at 4wks & 6.9+2.9% at delivery. In group A the mean rise in ferritin level was 72.6+10.5 5ug/l & in Group B it was 31.6+5.2ug/l.  In cases of iron Sorbitol 13.33% of the cases had severe reactions amounting to stop the injections & 60% had mild to moderate reactions continuing the injections. None of them developed severe reactions in Group A to stop the injections. The rise in parameters is statistically significant in both groups. Even though Iron Sorbtol is as efficacious as Iron sucrose in raising the Hb level, the Occurrence of more number of reactions restricts its use for intramuscular use. Iron Sucrose can be used as Observed Therapy ensuring definitive iron replenishment.

Keywords: Anaemia, Iron Sucrose, Parenteral Iron.

Title: A Comparative Study- Efficacy and Safety of Intravenous Iron Sucrose & Intramuscular Iron Sorbitol in Iron Deficiency Anemia during Pregnancies in Low Socio Economic Status

Author: Kadri Yogesh Bangera, Sujay Heranjal, Chethan K

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol. 3, Issue 1, April 2015 - September 2015

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A Comparative Study- Efficacy and Safety of Intravenous Iron Sucrose & Intramuscular Iron Sorbitol in Iron Deficiency Anemia during Pregnancies in Low Socio Economic Status by Kadri Yogesh Bangera, Sujay Heranjal, Chethan K