Abstract: Multisystem inflammatory syndrome in children (MIS-C) is a relatively new disease that came into existence after the COVID-19 pandemic. It is defined as a multisystem inflammatory condition post-COVID-19 infection due to an immune-mediated reaction of the body toward coronavirus. It is especially seen and defined in children, but this disease's underlying cause affecting a particular population is yet to be determined. Several hypotheses have been postulated which explain this disease as a result of immune dysregulation. The immune system responds to any infection by the B and T-cell response systems. This leads to antibody formation and cytokine production respectively. Some of the studies in the past have shown that the intensity of cytokines response in different age groups is different. The number of T-cells producing IL-2 and NK cells producing IFN-Y plays a huge role in an inflammatory response. Age group 1-21 yrs has shown to induce maximum cytokine response in studies which might be a possible explanation for the occurrence of MIS-C mostly in the children population.
Keywords: Multisystem inflammatory syndrome in children (MIS-C), cytokines, COVID-19.
Title: A possible explanation for the existence of multisystem inflammatory syndrome in children (MIS-C) only in the pediatric population
Author: Ashish Shrivastava
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 10, Issue 1, April 2022 - September 2022
Page No: 127-129
Research Publish Journals
Website: www.researchpublish.com
Published Date: 04-July-2022
