Abdominoperineal Resection in Rectal Cancer: Systematic Review

Abstract: Impaired perineal wound healing has become a significant clinical problem after abdominoperineal resection for rectal cancer. The increased use of neoadjuvant radiotherapy and wider excisions might have contributed to this problem the primary aim of this systematic review with meta-analysis was to determine the impact of radiotherapy and an extralevator approach on perineal wound healing after abdominoperineal resection for rectal cancer. The primary end point was overall perineal wound problems within 30 days after conventional or extralevator abdominoperineal resection with or without neoadjuvant radiotherapy. Secondary end points were primary wound healing, perineal hernia rate, and the effect of biological mesh closure on perineal wound problems. In conclusion neoadjuvant radiotherapy significantly increases perineal wound problems after abdominoperineal resection for rectal cancer, whereas the extralevator approach seems not to be of significant importance. Keywords: Abdominoperineal Resection, Rectal Cancer, increases perineal. Title: Abdominoperineal Resection in Rectal Cancer: Systematic Review Author: Abdullah Maher A Aqeel, Emad Saeed A Alzahrani, Fouad Ahmad Alsaadi, Adnan Yousef Tashkandi, Yaslam Nasser Yaslam Basrada, Rayyan Abdullah M Munshi, Abdulrahman Yousef Tashkandi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

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