Abstract: Antibiotics are highly powerful bioactive compounds which annul or restrict the growth of microorganisms. The unrestricted use of antibiotics has resulted in their emergence in the environment. Today, the whole of the world has acknowledged their presence in different natural and artificial systems. Surface waters (lakes, rivers, streams and sea), ground water, drinking water, soil, sediment and sludge have been reported for contamination with antibiotics. In the environment non-target microorganisms are inexorably exposed to antibiotics resulting in a potential risk of negative effects on indigenous microorganisms. Thus it is essential to monitor and assess the impact of antibiotics in the environment especially on microorganisms present. Therefore, this paper attempts toxicological characterization of antibiotics in order to investigate their probable toxic effects on microbial population. A bacterial short term bioassay viz. Pseudomonas fluorescens growth inhibition assay was used to determine the toxicological effects of three commonly used antibiotics procured from pharmacy stores located in Jaipur, Rajasthan (India).
Keywords: antibiotics, toxicity, growth inhibition, pollution, microbial assays.
Title: An Imperative Study on the Toxicological Evaluation of Three Antibiotics
Author: Smita Pareek, Nupur Mathur, Anuradha Singh, Amrita Nepalia, Pradeep Bhatanagar
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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