Abstract: Dyslipidemia is a lipid metabolism disorder characterized by increased or decreased lipid fractions in plasma. It is a risk factor for diseases still an essential problem in Indonesia, such as coronary heart disease (CHD). Curcumin is one of the compounds derived from turmeric extract, giving the turmeric plant its yellow color. Turmeric, with the scientific name Curcuma longa linn, is one of the spice plants and is also a medicinal plant. This study aims to analyze the anti-dyslipidemia effectiveness of turmeric ethanol extract (Curcuma longa) in Wistar male white rats. This type of research is an experimental Pre-test and Post-test group-only control design conducted in February 2023. Based on the results of these calculations, it can be concluded that a minimum of 4 male Wistar rats (Rattus norvegicus) are needed in each treatment group and analyzed by One-Way Anova if the data is usually distributed with further tests in the form of Post Hoc Tukey HSD test to see fundamental differences between treatments. However, as an alternative test, if the data were not normally distributed, the Kruskal-Wallis test was used. Turmeric (Curcuma longa) ethanol extract III significantly reduced total cholesterol compared to the control group (P value <0.05). Turmeric ethanol extract (Curcuma longa) III significantly reduced triglyceride levels compared to the control group (P value = 0.023). Turmeric ethanol extract (Curcuma longa) IV significantly reduced LDL levels compared to the control group (P value < 0.05). Turmeric ethanol extract (Curcuma longa) III significantly increased HDL levels compared to the control group (P value = 0.023). Turmeric ethanol extract (Curcuma longa) III significantly decreased SGOT and SGPT levels (P value < 0.05) compared to the control group.
Keywords: turmeric, anti-dyslipidemia.
Title: ANALYSIS OF THE EFFECT OF CURCUMA LONGA ETHANOL EXTRACT AS ANTI-DYSLIPIDEMIA IN MALE WISTAR RATS
Author: Wang Rui
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 11, Issue 1, April 2023 - September 2023
Page No: 270-275
Research Publish Journals
Website: www.researchpublish.com
Published Date: 22-September-2023
