Angiosarcoma, Classification, Histological Differentiation: Review

Tawfiq Zuhair Al Laylah, Ahmed Nasser Alghamdi, Mohammed Ibrahim Alotaibi, Raed Mohammed Alfaran, Othman Abdullah Alnemari, Ahmed Abdulghani Sindi, Mohammed Nawar Awadh Aljuaid, Rayan Azeb Rashed Alharthi, Nasser Awadh Saeed Alshehri, Ahmed Awadh Saee

Abstract: In this review we aim to give an overview of angiosarcoma from pathological aspects, we intended to focus of classification and pathogenesis and histological differentiation of each subtype, also to discuss the staging method of this type of soft tissue tumors. Databases: PubMed/ MIDLINE, and EMBASE were searched for articles published in English language with human subject up to January 17 2017. Literature search was performed to identified pathological studies that discussing the classification, pathogenesis, and histological differentiation of angiosarcomas. In addition to that, references found in identified articles were searched for more relevant studies. AS stem from any structural site in the body, many frequently the head and also neck, and breast cutaneous cells. Previous irradiation, harmful chemical exposure, as well as chronic lymphedema are determined as particular risk factors. Angiosarcoma could emerge in any type of soft-tissue structure or viscera as well as cutaneous angiosarcomas commonly entail the head and also neck, particularly the scalp. Angiosarcomas are of endothelial cell origin and tumours emerging directly from significant capillary or the heart are uncommon. Keywords: Angiosarcoma, classification, histological differentiation. Title: Angiosarcoma, Classification, Histological Differentiation: Review Author: Tawfiq Zuhair Al Laylah, Ahmed Nasser Alghamdi, Mohammed Ibrahim Alotaibi, Raed Mohammed Alfaran, Othman Abdullah Alnemari, Ahmed Abdulghani Sindi, Mohammed Nawar Awadh Aljuaid, Rayan Azeb Rashed Alharthi, Nasser Awadh Saeed Alshehri, Ahmed Awadh Saeed Alshehri, Manal Saeed Al Bogami, Maram Saeed Al Bogami, Majed Mansour Nawar Aljuaid International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Angiosarcoma, Classification, Histological Differentiation: Review by Tawfiq Zuhair Al Laylah, Ahmed Nasser Alghamdi, Mohammed Ibrahim Alotaibi, Raed Mohammed Alfaran, Othman Abdullah Alnemari, Ahmed Abdulghani Sindi, Mohammed Nawar Awadh Aljuaid, Rayan Azeb Rashed Alharthi, Nasser Awadh Saeed Alshehri, Ahmed Awadh Saee