Abstract: Crude exracts of Euphorbia hirta L. using different solvents like Ethanol, Dimethyl sulfoxide and Water have shown potential role in controlling harmful human pathogen Escherichia coli . Extracts and active principles from medicinal plants are one of the safest and ecofriendly methods for the treatments of various diseases. Medicinal plant Euphorbia hirta L. has been reported as antidiarrheal, antimicrobial, antioxidant, anticancer, and antidepressant for blood pressure. Antibacterial activity of ethanol, dimethyl sulfoxide and aqueous extracts of Euphorbia hirta L. were tested against test bacteria Escherichia coli using the agar disc diffusion method. Dimethyl sulfoxide extract of leaf and aqueous extract of bud were found to be more active, whereas ethanol extract of leaf, dimethyl sulfoxide extract of bud and aqueous extract of stem or leaf possessed moderate effect on the test bacteria. These results may suggest the distribution of antibacterial compound in aerial parts of Euphorbia hirta L. that can be explored for the isolation of bioactive compound.
Keywords: Euphorbia hirta L., Ethanol, Dimethyl sulfoxide, Aqueous and Escherichia coli.
Title: Antibacterial activity of Ethanol, Dimethyl sulfoxide and Aqueous extracts of Euphorbia hirta L.
Author: Indu Kumari
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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