Abstract: Gloriosa superba L. belongs to the family Colchicaceae. Locally known as Sengantha malar in Tamil, Glory Lily in English. It is a perennial climbing plant having a V-shaped tuber that is found all over India. The plant traditionally used for the treatment of several human diseases like cancer, piles, and purgative. But, it also initiated disorders and mortalities to humans due to purposeful and accidental poisoning. The seeds highly valued in the world market as sources of colchicine, a chemical that has used in a remedy against gout, skin related diseases and anticancer. The antibacterial activity of aqueous, methanol, chloroform and hexane extracts of the seed of G. superba determined by agar well diffusion method. The aqueous, methanol, chloroform and hexane seed extracts ere screened for their antimicrobial efficiency against gram-negative bacteria. Among the different solvent extracts, the antimicrobial activity was high in the methanol, extract followed by chloroform, hexane extracts. The antimicrobial activity was much less in the cold aqueous extract than boiled extract. The efficacy of antimicrobial activity depends on the nature and volume of active principles present in the tested extracts. The antimicrobial effect of the crude seed extracts is better than standard antibiotic drugs of ampicillin and tetracycline. The tetracycline showed a better inhibitory effect against E. cloacae, E. coli, K. aerogenes, K. pneumonia, S. typhimurium, S. maltophilia, B. megaterium, B. subtilis and gave low inhibitory effect in P. aeruginosa, P. maltophilia, P. oleovorans than seed crude extract of G. superba.
Keywords: Gloriosa superba, V- shape tuber, Seed, Antimicrobial activity, Ampicillin.
Title: Antimicrobial studies on seed extracts of Gloriosa superba L
Author: Babu Rao Karasala, Rajanikanth Garapati, Rajesh Govindan, Mani Rathinasabapathi Arulmozhi, Ramesh Narayanaperumal
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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