Abstract: Cancer is the second leading cause of death and in now a days Vegetable and fruit consumption is inversely associated with cancer incidence and mortality and Antioxidants from fruits and vegetables have been extensively studied for their free radical scavenging activities to prevent the occurrence of chronic degenerative diseases. The fruits which are high in polyphenols are reported to have antioxidant and chemotherapeutic potential. There is a major need for less toxic but yet effective therapies to treat cancer. Pomegranate has been shown to exert anticancer and antioxidant activity, which is generally attributed to its high content of polyphenols. This review provides that pomegranate targets a broad spectrum of genes and proteins to suppress cancer growth and progression it was shown that pomegranate juice (PJ) and/or pomegranate extracts (PE) significantly inhibit the growth of prostate cancer cells in culture and also inhibit cell proliferation and induce apoptosis in human breast cancer cells (MCF-7), human pancreatic cancer cells, Colon cancer (CACO) and in Hepato-cellular carcinoma (HepGII) cell lines.
Keywords: Pomegranate Juice, Breast Cancer, Human Pancreatic cancer, Colon Cancer, Hepato-Cellular carcinoma.
Title: Antioxidant and Anticancer Activity of the Pomogranate and Their Role in Cancer Prevention and Therapy
Author: Swathi Sudhakar, Dhivya Venugopal, Vignesh D, Karthikeyan S
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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