Abstract: Antithyroid drugs (ATDs) are a large group of medications that act on the metabolism of the thyroid hormones. They are associated with various side effects such as toxic hepatitis and leukopenia. We report two patients hospitalized at “Mother Teresa” University Hospital Centre in Tirana, Albania as Leukopenia from ATDs. Both patients were middle aged women, in treatment with ATDs that showed signs of fever, sore throat and mild muscular pain during their first examination. In their blood test resulted low white blood cells level and agranulocytosis. They were not taking other medication nor did they have other diseases. Excluding other confounding factors by differential diagnosis, it was concluded that it was their long treatment with ATDs the reason of Leukopenia. Interruption of the drug and close follow up were needed. In conclusion, ATDs were linked with serious side effects which should be considered in every patient with hyperthyroidism treated with this class of drugs.
Keywords: Antithyroid Drugs – Hyperthyroidism – Agranulocytosis – Fever – Differential Diagnosis.
Title: ANTITHYROID DRUG – INDUCED AGRANULOCITOSYS – A CASE SERIES
Author: Adela Haxhiraj, Edlira Elezi Buçpapaj, Violeta Hoxha
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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