Abstract: The role of the O-acetyl N-glycolyl neuraminic acid (O-acetyl NeuGc) specific lectin isolated and purified from the hemolymph of the freshwater crab Travancoriana charu in the innate immunity of the crab was documented using mammalian erythrocytes as antigenic stimulants. The erythrocytes when injected into the hemocoel regardless of their agglutinability and concentration, manifested increase in HA titer at varied time intervals. Augmentation in hemagglutinating activity, post administration of erythrocytes indicates an increase in the circulating lectin. Faster clearance of erythrocytes coated with lectin than the uncoated ones, indicates the role of lectin in the process of elimination of foreign pathogens. Lectins played an eminent role in enhancing hemocyte mediated hemolysis, functioning as an opsonin.
Keywords: Hemagglutinin, lectin, induction, clearance, Travancoriana charu.
Title: Biological role of the hemolymph lectin of the freshwater crab Travancoriana charu
Author: Sheeja V U, Basil Rose M R
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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