CHANGES IN CHLORIDE AND BICARBONATE CONCENTRATION IN THIRD TRIMESTER OF PREGNANCY IN NORMOTENSIVE AND PREECLAMPTIC PREGNANT WOMEN

Edebiri, O.E., Uche, O.K., Aigbokhai, A.O, Omogbemhe, S.A., Ogunleye, T.O., Ehiakhamen, D.O., Erhayanmen, O.M, Oyakhire M.O., Ikhajiangbe, H.I., Ohiwerei W.O.

Abstract: Increased  presence  of  serum  chloride  and Bicarbonate concentration in  preeclampsia may  bring  about  increased  osmolality leading  to  concealed  dilatation  of  vessels and One  of  the  probable  reasons  for  the increase  in  the  serum  bicarbonate  in  preeclamptic  group  could  be  a  decreased  pCO2 leading  to  suppression  of  vasodilatation. however,  the biochemical  changes  in  renal  function  accompanying normal pregnancies and preeclamptic pregnant women in Nigeria as a whole and south west Region  in  particular  are  not  well  documented This study examine Chloride and Bicarbonate concentration in third trimester of pregnancy in Normotensive and Preeclamptic pregnant women.  Thirty (30) pregnant women (15 normotensive and 15 preeclamptic women from Ondo town participated in the study. Five milliliters (5 ml) of venous blood was drawn from consenting participants and placed in a lithium heparin sample bottles for analysis. Result in fig 1 and figure 2 shows the serum levels of chloride and bicarbonate of normotensive pregnant women were (102 and 16mEq/L) respectively, where as in preeclamptic pregnant women were ( 104 and 18 mEq/L), however fig 1 show no statistically significant difference in chloride concentration in pre-eclamptic women compared to normotensive pregnant women (p>0.05) whereas Fig. 2 shows a statistically significant increase in bicarbonate concentration in pre-eclamptic women compared to normotensive pregnant women (p<0.05)

Keywords: Bicarbonate concentration, serum bicarbonate, preeclamptic pregnant women. 

Title: CHANGES IN CHLORIDE AND BICARBONATE CONCENTRATION IN THIRD TRIMESTER OF PREGNANCY IN NORMOTENSIVE AND PREECLAMPTIC PREGNANT WOMEN

Author: Edebiri, O.E., Uche, O.K., Aigbokhai, A.O, Omogbemhe, S.A., Ogunleye, T.O., Ehiakhamen, D.O., Erhayanmen, O.M, Oyakhire M.O., Ikhajiangbe, H.I., Ohiwerei W.O.

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Vol. 10, Issue 2, October 2022 - March 2023

Page No: 256-259

Research Publish Journals

Website: www.researchpublish.com

Published Date: 21-March-2023

DOI: https://doi.org/10.5281/zenodo.7755874

Vol. 10, Issue 2, October 2022 - March 2023

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CHANGES IN CHLORIDE AND BICARBONATE CONCENTRATION IN THIRD TRIMESTER OF PREGNANCY IN NORMOTENSIVE AND PREECLAMPTIC PREGNANT WOMEN by Edebiri, O.E., Uche, O.K., Aigbokhai, A.O, Omogbemhe, S.A., Ogunleye, T.O., Ehiakhamen, D.O., Erhayanmen, O.M, Oyakhire M.O., Ikhajiangbe, H.I., Ohiwerei W.O.