Abstract: We assessed the relationship of hemoglobin (Hb) levels with bone mineral density (BMD) by detected dual-energy X-ray absorptiometric (DXA) method in a large sample of men. The study conducted with 269 men, who were screened for osteopenia or osteoporosis by DXA. Patients categorized with osteopenia or osteoporosis (T score<-1.0 SD) were grouped as having low bone mass (LBM).Anemic patients were older and had significantly higher ratio of diabetes. In the study cohorts Anemic patients (n = 45) when compared with normal Hb subjects (n = 224), they had significantly higher ratio of patients with low bone mass (64.4% vs. 46.9%; p = 0.031, respectively). We found no statistically significant difference of femur T-score, femur BMD, femur Z-score, spinal T-score, spinal BMD and spinal Z-score between groups. There were significant correlations between Hb values and spine T- score, spine BMD values of the anemic patients in bivariate correlation analysis (r = 0.319; p = 0.033, r = 0.310; p = 0.038, respectively). In conclusion, we have shown that anemic men had significantly high prevalence of subjects with low bone mass. This means that anemia has a rule as a risk factor in changes of bone turnover leading to decrease bone density.
Keywords: Bone turnover- osteopenia- osteoporosis-hematology.
Title: Changes in Hematological Markers Associated With Bone Turnover in Male Subjects
Author: Fawzi A. Oraibi, Jalaludden A. Khan, Mohammed S. Ardawi
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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