Characterization of the Leukaemia-Associated ETO Homologous

Khaled Rhafiq Shabrawy, Raghad Yaser Shawoosh, Abdulkader Mahmoud Dadou, Sally Shaker Alkhonizi, Rawan Alqurashi

Abstract: MTG16, MTGR1 and ETO are nuclear transcriptional corepressors of the human ETO protein gang. MTG16 is ensnared in hematopoietic improvement and in controlling megakaryopoiesis. Moreover, ETO homologue qualities are 3'participants in leukemia combinations created by chromosomal translocations mindful of hematopoietic dysregulation. The proposed cooperations of the ETO homologues may have suggestions for the onset of leukemia, since it opens up for an AML1-ETO interceded aggravation of ETO homologue capacity and a regulation of AML1-ETO capacity by the ETO homologues. In this review we tried to identify the outcomes of several reviews that are discussing Characterisation of the leukaemia-associated ETO homologous. Keywords: Leukaemia-Associated ETO Homologous, AML1-ETO. Title: Characterization of the Leukaemia-Associated ETO Homologous Author: Khaled Rhafiq Shabrawy, Raghad Yaser Shawoosh, Abdulkader Mahmoud Dadou, Sally Shaker Alkhonizi, Rawan Alqurashi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 3, Issue 2, October 2015 – March 2016

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Characterization of the Leukaemia-Associated ETO Homologous by Khaled Rhafiq Shabrawy, Raghad Yaser Shawoosh, Abdulkader Mahmoud Dadou, Sally Shaker Alkhonizi, Rawan Alqurashi