Abstract: Low bone density and chronic bone aches pain of unknown causes are common in sickle cell disease (SCD) adult patients. Chronic bone pains, osteoporosis, bone fractures, and muscle weakness can result fromvitamin D deficiency (VDD). Previous reports indicate a relation between VDD in SCD; however, the clinical correlates have not been well described. We therefore did a cross sectional survey to assess whether there is any correlation between Vitamin D deficiency and bone pain in patients with SCD.
Results: Our results showed significant association between bone lesions and pain. However we could not demonstrate the correlation between VDD and bone pain in patients with sickle cell disease as the data was not available.
Conclusions: We therefore suggest Clinicians attending SCD patients with chronic musculoskeletal pain should be aware of and screen for markers of bone turnover to detect the extent of VDD.
Keywords: sickle cell disease (SCD), chronic musculoskeletal pain.
Title: Chronic Pain in Sickle Cell Disease and Vitamin D Deficiency
Author: Abdulaziz Khalid Althafar, Fahad Salman Al Harbi, Khalid Majid Al Khaldi, Mohammed Sami Al Haddad, Mahdi Youssef al Youssef, Muthana Abdullah al Sahlawi, Abdulrahman Ahmad Al Naim, Adel Nasser Al Bargi, Sayed Ibrahim Ali
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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