Abstract: Psoriasis is a chronic systemic inflammatory disease with a frequency of 2-3% in Europeans, and approximately 8% in specific Nordic countries. Plaque psoriasis (psoriasis vulgaris) is the most common type of psoriasis accounting for 90% of all cases, and roughly 70-80% of all patients are considered to have mild psoriasis that can be managed with topical treatment alone. This systematic review study aimed to discuss the clinical features, incidents, and treatment approaches for psoriasis worldwide, through review the literature and including most important studies that concerning psoriasis from the aspects which are mentioned previously. Comprehensive searches of Medline, Embase, Cinahl and The Cochrane Library were conducted and last updated on December 2016, restricted to articles published in English. systematic literature search was conducted according to a predefined protocol for randomized, placebo-controlled or reviews studies and Prior guidelines on psoriasis were also evaluated that were discussing the 3 aspects of our study which are, Clinical features, Epidemiology, and Treatment of psoriasis. Topical treatments are appropriate for patients who are candidates for localized therapy however might not be useful as monotherapy for many patients who are prospects for systemic and/or phototherapy, where standard systemic treatments, including methotrexate, CyA, narrowband (NB) and broadband UVB, PUVA, oral retinoids, and the newer biologic agents are recommended.
Keywords: Psoriasis, patients, systematic review, Topical treatments, UVB, PUVA, oral retinoids,
Title: Clinical Features, Epidemiology and Treatment Approaches of Psoriasis; Systematic Review
Author: Naifah khalaf zitoon alanazi, Ruba abdulqader alrehaili, Rawan ahmed salem alnufaiee, Asrar abdullah albasi, Sarah Naif Alsayil, Atheer Thamer Alsaedi, Faris Thamer Alsaedi, Masoumah Redha Alawami, Shayan Mohammed ALraddadi, Samar ali sager alamri, Aminah Abdulghany Sabbagh
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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