Abstract: Colistin is an antibiotic for treating various multidrug-resistant Gram negative bacteria. It is at present the last-line drug for infections caused by Gram negative bacteria. Colistin resistance is a concerning issue because of lack of development of new antibiotics. Bacteria like Pseudomonas aeruginosa, Enterobacteriaceae members such as Escherichia coli, Klebsiella spp. have an acquired resistance towards colistin. Due to the high occurrence of colistin-resistant Enterobacteriaceae in waste water and process waters from sources like slaughterhouses, hospitals were considered as the hotspot for the colistin resistances (mcr) genes. Clinicians should be aware about the possibility of the development of colistin resistance among many multidrug resistant bacteria via adaptations and mutation mechanisms. Rapid growth of bacterial resistance has made it quite tough for us to depend on the development of new antibiotics for which, logical approaches need to be used for utilizing old antibiotics like colistin, to deal with rising issues of colistin resistance.
Keywords: Colistin resistance, Enterobacteriaceae, Gram negative bacteria.
Title: COLISTIN RESISTANCE IN ENTEROBACTERIACEAE THROUGH SEWAGE SAMPLES/WATERBODIES
Author: AVISKAR PARHI, Dr. NAMITA BEDI
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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