Abstract: Obesity and Vitamin D deficiency are now considered morbidity phenomenon prevalent in the whole world. Moreover, obese subjects are known to have lower vitamin D levels compared to non-obese subjects. The objectives of the current study are to estimate the prevalence of obesity and vitamin D status in women living in Jeddah, Saudi Arabia and to find the correlation between serum [25(OH)D] and BMI in Saudi women, in addition to predict the serum vitamin D status in obese women. Two hundred seventy one Saudi women, aged between 20-40 years were included with this study. Studied subjects visited the clinic of the Center of Excellence for Osteoporosis Research (CEOR), during November 2013 to September 2014 and measured their fat distribution by dual energy X-ray absorptiometry (DXA). Women were stratified according to their body mass index (BMI) into overweight with 25-<30 kg/m2 and obese with BMI ≥30 kg/m2. Women provided their blood samples to detect Serum [25(OH) D]: a value of < 24.9 nmol/L is considered as deficiency, insufficiency 25 to 74.9 nmol/L and sufficient ≥75 nmol/L. The results of the present study showed that obesity was estimated by 52.1% (29.2% overweight and 22.9% obese) by using BMI method. Anthropometric characteristic (height is excluded), fat distribution and body composition revealed a significant increasing at P< 0.0001. High prevalence of vitamin D deficiency and insufficiency were reported in all studied women (47.6% and 44.3%, respectively), regardless of BMI. The same finding of vitamin D deficiency and insufficiency were found when the women stratified according to their BMI, in control group (43.8% and 46.9%, respectively), overweight group (44.3% and 49.4%, respectively) and obese group (59.7% and 32.3%, respectively). Furthermore, our result showed that serum [25(OH)D] has no significant difference between the studied women in relation to their BMI unless the women were stratified according to vitamin D status into deficiency, insufficiency and sufficiency; After this stratification, a negative association was found between serum [25(OH)D] and BMI for only the sufficient group in obese women. In conclusion, the present study has demonstrated that vitamin D deficiency and insufficiency are rather highly prevalent among women living in Jeddah, Saudi Arabia; and this prevalence is becoming worse with obesity.
Keywords: Vitamin D- BMI- DXA- Obese- Women- Jeddah.
Title: Correlation between Serum Vitamin D Status and Body Mass Index in Obese Women
Author: Mai Albaik, Jalaluddin Khan, Mohammed-Saleh Ardawi, Said S. Moselhy
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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