Abstract: Obesity and Vitamin D deficiency are now considered a morbidity phenomenon prevalent in the whole world. Moreover, obese subjects are known to have lower vitamin D levels compared to non-obese subjects. The objective of the current study is evaluate vitamin D status in obese women in Saudi Arabia through serum [25(OH)D] and to predict the factors that contribute to vitamin D influence. Moreover, predictive model for body mass index (BMI) was built for Saudi women.Two hundred seventy one Saudi women, aged between 20-40 years, living in Jeddah, Saudi Arabia were conducted with this study. Women were stratified according to their body mass index (BMI) into overweight with 25-<30 kg/m2 and obese with BMI ≥30 kg/m2.The results of the present study showed that prevalence of obesity was estimated by 52.1% (29.2% overweight and 22.9% obese) while the prevalence of vitamin D deficiency and insufficiency in control group (43.8% and 46.9%, respectively), overweight group (44.3% and 49.4%, respectively) and obese group (59.7% and 32.3%, respectively) giving overall deficiency and insufficiency in all women (47.6% and 44.3%, respectively) regardless of BMI. Furthermore, our result showed that serum [25(OH)D] has no significant difference between the studied women in relation to their BMI unless classifying our data to three vitamin D levels into (deficiency serum [25(OH)D] <24.9, insufficiency 25-74.9 and sufficiency ≥75 nmol/L). After this classification, a negative association was shown between serum [25(OH)D] and BMI for only the sufficient group in obese women. However, our results showed that serum [25(OH)D] was presented as a predictive factor of obesity at (P< 0.018, importance 8%) with accuracy (91.7%). The significant variables arranged in descending order of importance were as follows: Tissue fat (22%), HC (19%), BMC (17%), fat free (11%), A/G ratio (10%), serum [25(OH)D] (8%), WHR (5%),
Tissue (4%) and LDL (4%).In conclusion, the present study has demonstrated that vitamin D deficiency and insufficiency are rather highly prevalent among Saudi women regardless obesity. Obese women are advised to control their weights and to do routine vitamin D assessment.
Keywords: Obese- bone health- vitamin D
Title: Correlation between Serum Vitamin D Status and Bone Health in Obese Women
Author: AlbaikMM, Jalal JA, Ardawi MS, Said S. Moselhy
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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