CORRELATION OF AGE AND SEX IN RELATION TO SERUM CALCITONIN, CREATININE AND URIC ACID ON CKD PATIENTS WITH THYROID ABNORMALITY COMPLICATION

Christian Ugege, Eidangbe, A.P, Olaniyi O.D., Ogedegbe, I.S, Ohiwerei W.O., Otaye, O.M

Abstract: This study evaluated the serum calcitonin, creatinine and uric acid levels in chronic kidney diseases (CKD) complicated by dysthyroidism. A total of 119 participants were recruited in this study, majority of who were males. Majority of the participants in this study were between the ages of 30 to 68 years with a median of 49 years. The high prevalence of CKD among this age group can be attributed to underlying pathologies such as hypertension, diabetes or both. The level of serum calcitonin, T₃, T₄, TSH,creatinine and uric acid of study participants according to age range, for age < 20 years, Calcitonin(126±23.9), T₃(0.800±0.0741), T₄(6.79±0.296), TSH (8.41±1.48), Creatinine (11.1±1.29), Uric Acid (21.1±2.55), for age 21 - 40 years, Calcitonin(145±42.0), T₃(0.763±0.0565), T₄(7.75±0.701), TSH (8.64±1.43), Creatinine (7.91±1.29), Uric Acid (14.0±1.77). for age > 41 years, Calcitonin(71.2±11.3), T₃(0.765±0.0396), T₄(7.45±0.255), TSH (8.11±0.529), Creatinine (7.01±0.66), Uric Acid (13.4±0.801).from the result of this study calcitonin, creatinine and uric acid proved to be statistically significant (p≤0.05), however T_3, T_4,TSH showed no statistical significance.