Abstract: Background: Systemic lupus erythematosus (SLE) is an autoimmune disease. (SLE) has many different skin lesions due to SLE can produce serious range of morbidity resulting from painful skin lesions, Some of the cutaneous manifestations for SLE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, cutaneous mucinoses, and cutaneous calcinosis, they maybe specific to SLE but also they could be associated with different dermatological diseases such Eczema. Objective: There are several studies that had already discussed a very important point concerning this topic but the aim of this paper is to evaluate the symptoms on the skin caused by SLE based on a previous different studies. Methodology: the methods of this study will be based on a systemic analysis and literature search through US national library Midline (pubmed) all these studies which discusses the coutanous or skin symptoms of SLE will be included in this study. Results: Skin involvement, including the rare variant of TEN-like acute cutaneous SLE, is very common among SLE patients. The acute syndrome of pan-epidermolysis or apoptotic pan-epidermolysis may become a useful designation when considering a clinical diagnosis of drug-induced TEN or SLE. Further studies are required to verify our findings. Conclusion: Skin disease in patients with lupus erythematosus may be subdivided into two broad categories - those lesions that when biopsied demonstrate interface dermatitis and those that do not demonstrate interface dermatitis. The skin lesions that are represented by the interface dermatitis include discoid lupus erythematosus, subacute cutaneous lupus erythematosus and acute cutaneous lupus erythematosus. Patients with these 'specific' manifestations have varying degrees of systemic involvement from rare systemic disease in patients with localized discoid lupus erythematosus to common and often severe involvement in patients with acute cutaneous lupus erythematosus.
Keywords: cutaneous mucinoses, Systemic Lupus, erythematosus (SLE), Skin involvement.
Title: Cutaneous Manifestations of Systemic Lupus Erythematosus (SLE)
Author: Haneen Mohammed Sibieh
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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