Abstract: A 45 year old male patient diagnosed case of chronic myeloid leukemia (CML) in 2003 being treated with dasatinib since 2010 came to the emergency department with complaints of fever, cough and breathlessness. On examination bilateral pedal edema was present and chest X-ray showed right sided pleural effusion. Pleural tap has been done with which his breathlessness was improved. Patient was initially started on antibiotics but not responded to the therapy. Now pleural effusion was considered as dasatinib induced and started on a trial of low dose oral prednisolone. Then patient shown improvement dramatically and successfully treated with short course of low dose oral prednisolone.
Keywords: Imatinib resistant, chronic myeloid leukemia, tyrosine kinase inhibitors, pulmonary arterial hypertension.
Title: DASATINIB INDUCED PLEURAL EFFUSION TREATED WITH LOW DOSE PREDNISOLONE
Author: Dr. Kavitha Saravu, Dr. Pradeep Kumar Reddy Sura, Dr. Barkur A. Shastry, Dr. Ajit Singh
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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