Delayed thyroid function in preterm infants especially in low weight birth Infants

Manal Salem Alsaiari, Najood Rahim Alenezi, Mariam Gryan Alenezi, Anfal Ma'di Alsha'lan, Wafa Owied al shammri, Mashael Abdulateef Mustafa, Sarah Jamal Alkhannani, Wasan lafi alanazi, Fahad Ali AlZahrani, Abdulkarem Dhahawi Alruwaili, Amjed Naeem Alrw

Abstract: Hypothyroidism is more typical in preterm infants than in term infants, particularly in sick preterm infants. Preterm infants have lower levels of tri-iodothyronine (T3) and free thyroxine (T4) than term infants during the very first several weeks, which is more extreme in the tiniest and least fully grown preterm infants. Therefore, this systematic review study aimed to evaluate the delayed thyroid function in newborns especially in low birth weight (LBW), from different aspects, also we aimed to discuss the complications that occur in consequence to this condition. We conducted our electronic search for relevant articles through several databases such; PubMed (MIDLINE), EMBASE, and GOOGLE scholar, up to December 2016, this searching for articles was done by combining the search terms premature*, preterm, low birth weight, thyroid function. Then lists of published articles were hand-searched to identify additional relevant studies. Thyroid dysfunction is frequently observed among the comorbidities related to prematurity. An immature hypothalamic-pituitary-thyroid axis, postnatal exhaustion of thyroid stores, non-thyroidal health problem, and administration of drugs (such as dopamine and steroids) can all lead to derangement in thyroid function in preterm newborns. Many aspects, taken together, might represent high danger conditions for thyroid problems that can impact these children in the neonatal duration as well as later on in life. Keywords: Hypothyroidism, tri-iodothyronine. Title: Delayed thyroid function in preterm infants especially in low weight birth Infants Author: Manal Salem Alsaiari, Najood Rahim Alenezi, Mariam Gryan Alenezi, Anfal Ma'di Alsha'lan, Wafa Owied al shammri, Mashael Abdulateef Mustafa, Sarah Jamal Alkhannani, Wasan lafi alanazi, Fahad Ali AlZahrani, Abdulkarem Dhahawi Alruwaili, Amjed Naeem Alrwaili, Ahmad foad ahmad basehi International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Delayed thyroid function in preterm infants especially in low weight birth Infants by Manal Salem Alsaiari, Najood Rahim Alenezi, Mariam Gryan Alenezi, Anfal Ma'di Alsha'lan, Wafa Owied al shammri, Mashael Abdulateef Mustafa, Sarah Jamal Alkhannani, Wasan lafi alanazi, Fahad Ali AlZahrani, Abdulkarem Dhahawi Alruwaili, Amjed Naeem Alrw