Abstract: Bipolar Illness (BD) has an around the world life time frequency of about 2.4% reported throughout Americas, Europe, Asia, Middle East and New Zealand. The course of BD is relentless and characterised by recurrent state of mind episodes creating considerable dysfunction in the impacted individual. Worldwide, the disorder ranks 5th in contributing to a loss of working and imparts significant individual and societal issue. The South Asian area homes one-fifth of individuals with mental illness around the world and yet, much stays to be explored concerning the dominating course patterns of BD in Asia and the associated elements Scientists have in fact kept in mind a fairly higher frequency of BD-I amongst those with Asian ethnic background when compared with the Caucasians. The present review determines the local qualities of BD course patterns and the involved elements. Regional and cross-national studies expose a mania-predominant course in BD in Asian nations. Extended depressive episodes and comorbid stress and anxiety disorders intensify the course of BD-II. Particular threat factors such as the young age of start and higher episode frequency are useful predictors of bipolar diatheses. Substance use disorder comorbidity is more common in males whereas anxiety and suicidal behaviours are more frequent in women with BD. Comorbid stress and anxiety and personality disorders likewise encumber the health problem course. Logistic reasons and lack of knowledge of side-effects were specifically related to poor adherence. An 'eveningness' chronotype and bad sleep quality were connected with regular recurrences. Seasonal patterns vary amongst ladies and males, particularly for depressive episodes. There are region-specific attributes in bipolar illness course and aspects influencing such course patterns compared to the remainder of the World. Future research from Asia will try to study the neurobiological underpinnings of such attributes and plan appropriate methods to deal with the same.
Keywords: Bipolar Illness (BD), region-specific attributes, neurobiological underpinnings.
Title: Diagnosis and Management of Bipolar Disorders in Primary Care
Author: Abdullatif Alhassan A Fathi, Faisal Khalid A Zakri, Hassan Ahmed Hessain Musawi, Mohammed Mughabbish Thafrani, Ahmed Ibrahim Ibrahim Alkhawaji, Abdulaziz Hassan K. Almahdi, Ahmed Abdullah Ahmed Hakami
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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