Abstract: The main objective of this review was to evaluate and discuss the evidence related to pathogenesis, diagnosis and therapeutic approaches to the osteomyelitis, also to emphasize the risk factors and causes of this serious bone disease. MEDLINE, EMBASE, and Google scholar databases were used in detailed search for relative articles concerning osteomyelitis in any clinical aspect, but restricted to only English language published articles up to May,2017. Furthermore, references of these articles were searched for more relevant studies that could contribute in our review. Osteomyelitis is a major infection connected with substantial morbidity. The occurrence is increasing with the occurrence of diabetes. High clinical suspicion is essential to early diagnosis, and recognition of the pathogen is essential for management. MRI has the greatest diagnostic precision amongst radiological studies. Antibiotic routines for the empiric treatment of acute osteomyelitis, especially in children, need to consist of an agent directed versus S. aureus. Betalactam prescription antibiotics are first-line alternatives unless MRSA is believed. If methicillin resistance amongst community isolates of Staphylococcus is greater than 10 percent, MRSA must be considered in preliminary antibiotic protection. In some situations, it may not be possible to securely eliminate a piece of contaminated prosthetic product, or a sequestrum of lethal bone. In such cases, it might be necessary to prescribe an oral antibiotic for long-lasting suppression of infection.
Keywords: Osteomyelitis, therapeutic approaches, English language published articles.
Title: Diagnosis and Therapeutic Approaches for Osteomyelitis, Review
Author: Nuha Hazem Bukhari, Abdullah Mohammedalsasi A Alawamir, Abdullah Sabti S Almoeirfi, Sultan Mursi Albogami, Salah Ghazi S Almatrafi, Abdulrhman Mohammed Almehmadi, Ali Hassan Altrabolsi, Khaled Saad Mohammed Alboaqami
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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