Diagnosis and Treatment Options of Anaplastic Oligodendroglioma

Afraa Salama Alenezy, Woroud Mohammed Alharthi, Eida Mohammed Alharthi, Asmaa Fawzi Hijji, Rowa Fahad Arqasous

Abstract: Oligodendroglial tumors are the least typical of the gliomas, accounting for 3% to 20% of all glial growths [Class III] Of these, roughly 70% are low-grade OD and 30% are AOD. This systematic review study aimed to evaluate the diagnosis approaches and differential diagnosis of oligodendroglioma and specifically anaplastic type AOD. We also aimed to discuss the treatment options of this type of brain tumors through reviewing the evidence based trails. A literature search was conducted through December 2016. The following databases were searched: PubMed (MIDLINE), Embase, Cochrane, and ScienceDirect. For each database mesh of terms were used in searching included: “glioma” or “primary brain tumor” or “brain cancer” or “malignant brain tumor” or “anaplastic oligodendroglioma (AOD)” or “AOD;” Combined with Diagnosis AND Treatment. We also search the references of every included articles to find more relevant studies discussing the same topic as our study aimed to discuss. Oligodendrogliomas are amongst the most checked out tumors of the nerve system. Despite the considerable deadly potential of these tumors, a significant number has actually been revealed to react well to treatment. The positive effect of combined early radiotherapy and PCV chemotherapy for AO and blended kinds, anaplastic oligoastrocytomas with 1p/19q co-deletion, has just recently been clearly demonstrated. An equally considerable or more positive effect of often utilized temozolomide has actually not yet been proven. Keywords: Oligodendroglial tumors, PubMed (MIDLINE), Embase, Cochrane, and ScienceDirect. Title: Diagnosis and Treatment Options of Anaplastic Oligodendroglioma Author: Afraa Salama Alenezy, Woroud Mohammed Alharthi, Eida Mohammed Alharthi, Asmaa Fawzi Hijji, Rowa Fahad Arqasous International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Diagnosis and Treatment Options of Anaplastic Oligodendroglioma by Afraa Salama Alenezy, Woroud Mohammed Alharthi, Eida Mohammed Alharthi, Asmaa Fawzi Hijji, Rowa Fahad Arqasous