Abstract: This is a retrospective study of 316 cases of prostatic diseases investigated at the department of histopathology, Federal Medical Center, Owerri , from 2012-2014.Retrieved data included age, PSA, and DRE findings. Mean age of patients was 70.6 years, while that of PSA findings was 37.9ng/ml.43% of the cases was positive for Pca with mean of age and PSA respectively 71.6 years and 51.2ng/ml.BPH was demonstrated in 44.6% with mean of age and PSA respectively 69.5 years and 29ng/ml.5.6% of the abnormal DRE have PSA values below the threshold-4ng/ml ,while the rest was above 4ng/ml. Only a single case of prostatic carcinoma was detected with PSA below 4ng/ml. The peak age of incidence of both BPH and Pca, together with abnormal DRE and PSA, all have highest frequency at 71-80th decade of life. The sensitivity, specificity, and positive predictive value of PSA were 98.4%, 14.2% and 47.4% respectively, while that of DRE were 39.4%,57.2%, 41.3% accordingly. Prostatic neoplasm, commonly existing at 7th to 8th decade of life, can be investigated with the synergistic support of PSA and DRE. While PSA in the study was comparatively impressive in performance, deployment of trained personnel will engender improvement in DRE.
Keywords: Digital Rectal Examination, Prostate Specific Antigen, Hyperplasia, Carcinoma.
Title: Diagnostic Performance of DRE& PSA in Prostatic Disease Investigations: An Experience at Federal Medical Center, Owerri
Author: Bernard Kafor, Kingsley Anochiwa, Godfrey Nnadi.
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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