Abstract: Diaphragma sellae is a dural fold which extends over the pituitary fossa. It includes a defective area in its center, the diaphragmal opening, which transmits the pituitary stalk. In cases of pituitary adenoma, macroadenoma of large size tends to elevate the diaphragma sellae and may perforate it.
Objectives: To study the dimensional changes of the diaphragma sellae opening between the diaphragmal opening dimensions and to correlate that dimensional change with volumetric data changes before and after the operation.
Materials and Methods: 72 cases were retrospectively enrolled in this study. The imaging data before and after the operation was revised. MITK, an open source software from MINT MEDICAL, was used to process the imaging data of these cases.
Results: There is a highly significant statistical relationship between the diaphragma sellae width and the pituitary adenoma total volume before the operation. The same occurred with the tumor volume above the level of the diaphragma sellae opening. On the other hand, there was a statistically non-significant correlation between the residual tumor volume and the width of the diaphragmal opening.
Conclusion: According to our results, presence of residual adenoma is not necessarily to be above the diaphragma sellae. The statistically non-significant correlation is due to the parasellar extension, which was the main cause of residual tumor presence in our specimen.
Keywords: Diaphragmal opening, Pituitary adenoma, Transsphenoidal surgery.
Title: Dimensional Changes of Diaphragma Sellae Opening In Transsphenoidal Pituitary Adenoma Surgery
Author: Ahmed Abdelmaksoud, Peng Fu, Osamah Alwalid, Ahmed Elazab, Ahmed Zalloom, Wei Xiang, Xiaobing Jiang, Hongyang Zhao
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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