Abstract: DNA is a stable and biocompatible molecule due to its chemical and physical properties. Recent advancements in DNA nanotechnology allow the application of DNA origami nanostructures in a wide range of biomedical settings. The methods for the design, synthesis and analysis of DNA origami nanostructures are discussed in this study. One of the major applications of DNA nanotechnology is in therapeutics, as a delivery vehicle for chemotherapeutic drugs (such as doxorubicin and daunorubicin), as well as applications in photothermal and photodynamic therapy, all of which are discussed in this study. The study also discusses design parameters that need to be taken into consideration for the suitability and efficacy of the DNA origami nanostructures for different therapeutic functions.
Keywords: DNA origami, Nanostructures, Drug delivery, Photothermal, Photodynamic.
Title: DNA Origami and its Applications in Therapeutics
Author: Arya Mosahab
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Vol. 11, Issue 1, January 2023 - March 2023
Page No: 79-85
Research Publish Journals
Website: www.researchpublish.com
Published Date: 23-March-2023
