Abstract: The preset study supports previous finding that Vitamin A can induce and accelerates lens regeneration in pigmented epithelial calls (PECs) of dorsal iris in Swiss albino mice. In Lens regeneration, several workers shown that Vitamin A possess the mitogenic activity which causes functional impairment of retinoid receptors and thereby inhibits the lens regeneration. The purpose of present study to understanding the DNA base pair difference between normal lens and regenerated lens DNA. The work was mainly based on histological and molecular aspects of lens regeneration. The study concludes that the base pairs of regenerated lens DNA and normal lens DNA were almost similar except these SNPs. There may be some mutation or aberration of DNA base pair alignment present in regenerated DNA base pair compare to normal DNA base pair.
Keywords: Pigmented epithelial calls (PECs), DNA, Young Swiss Albino Mice.
Title: DNA Sequencing of Regenerated Lens under the Influence of Vitamin - A In Young Swiss Albino Mice
Author: Vikram Singh Bhati
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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