Abstract: Ethion an organophosphate was orally administrated at 16mg/kg/day to Swiss albino mice for 5, 10, 20 and 30d days, control mice received similar. Quantities of olive oil. Daily body weight were recorded and the mice sacrificed by cervical dislocation after 24 hours the terminal exposure of ethion, in the number of follicles, and histological evaluation of the control mouse, ovary, revealed the presence of many developing follicles Graafian, corpora luteal and Atretic follicles the treatment with ethion foe 5 and 10 d showed no significant changes in the number of small ,medium and large healthy and atretic follicles how ever there was significant decrease in the Total number of healthy follicles with d ethion treatment the histological evaluation of the ovary of mouse following Ethion Treatement for 5d revealed the presence of many developing follicles, corpora luteal and atretic follicles treated and Treatment with Ethion for 20,30,d showed a significant decrease in the number of small, medium, large and total number of atretic follicles when compared with control. The histological evaluation of the ovary of the mice following Ethion treatment for 20, 30 d showed developing follicles, corpora luteal many atretic many atretic follicles but not Graafian follicles There was a decrease in the ovary uterus. Weight, protein, sialic and 3βHSD content, but there was increase in the cholesterol content in treated mice compared to control.
Keywords: Ethion. Histology, ovary, enzymes, Toxicity.
Title: Effect of Ethion Administration Schedules on Estrous Cycle and Follicular Dynamics in Albino Mice
Author: SUVARNARAJESH.YADAPPA.KRISHNAPUR, B.B.KALIWAL, M.F.ANSARI
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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