Abstract: The roles of various drugs have been investigated on blood glucose. However, the effect of Septrin(co-trimoxazole) on blood glucose have not received much attention. The present study investigated the effect of Septrin (co-trimoxazole) on blood glucose in male albino Rats. A total of fifteen (15) Rats were used for this study and grouped into three (3) classes labelled A, B and C. Group A and B consist of Septrin treated Rats and group C consists of the control group. Co-trimoxazole was given for five (5) days. After five (5) days of administration, the animals were sacrificed. Blood sample of Rats were collected in Heparin bottles and biochemical analysis was carried out for the determination of blood glucose. There was a significant decrease blood glucose level among the treated group. This decrease was observed with an initial dose of 4.4mg/kg body weight of Co-trimoxazole when compared with the control. The results suggest that Septrin is safe for use for a diabetic patient or hyperglycaemic person. It also suggests that Septin should be taken postpandrially.
Keywords: Septrin, blood glucose, hypoglycaemia, weight loss.
Title: Effect of Septrin (Co-Trimoxazole) On Blood Glucose of Wistar Albino Rat
Author: T.O OLADUN, E.O TAIWO
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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