Abstract: The antibacterial activity of three local Yemeni honey brands (Sidr, Maraiy and Somor honey) and antibiotics (Gentamicin and Doxycyclinehyclate) were investigated by agar well diffusion method against four standard bacteria isolates; Escherichia coli ATCC 10536 (E. coli), Staphylococcus aureus ATCC 29737 (S. aureus), Pseudomonas aeruginosa ATCC 25619 (P. aeruginosa) and Salmonella abony ATCC6017 (S. abony) and comparative these with the effectiveness of antibiotics blended with honey on the growth of all used standard bacteria. All diluted honey brands (25%, 50% and 75%) inhibit growth of 3 standard bacteria (S. abony, S. aureus then E. coli), while P. aeruginosa gave moderate growth with effect on its pigment production. The inhibitory effect of Gentamicin on test organisms was inhibit growth of S. aureus (17.5 mm), S. abony (15 mm) and P. aeruginosa (6.5 mm). Mixture of Gentamicin and honey brands showed maximum inhibitory zones (sensitivity) with S. abony and S. aureus then P. aeruginosa were 32, 30 and 16 mm; respectively. Whereas Doxycycline hyclate was not effective on the tested organisms except S. aureus which showed high sensitivity (30-32 mm) when blended Doxycycline hyclate with samples of honey. The obtained results in this study approved mixture of honey and antibiotics having antibacterial potency able to establish valuable inhibition zones in vitro and they were higher in inhibition values than the reference drugs. In conclusion, honey (a natural product) could effectively complement standard antibiotics, especially in cases of pathogenic infections in wounds in general and in burn wounds in particular, with beneficial healing effects.
Keywords: Yemeni honey, Antibiotics blended with honey, Pathogenic organisms.
Title: Effectiveness of Antibiotics Blended With Honey on Some Pathogenic Bacteria Species
Author: Salwa H. Alkhyat, Maher Ali Al.Maqtari
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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