Abstract: Turmeric (Curcuma longa Linn or Curcuma domestica Val) belongs to the Zingiberaceae family. People have long known it as a plant with many benefits, such as anti-inflammatory, anticancer, antioxidant, antiulcer, and antibacterial. This study aims to analyze the effectiveness of turmeric (Curcuma longa) extract 50% with 90% in accelerating wound healing time after tooth extraction in Wistar rats. This experimental laboratory study used a complete randomized design with a post-test-only control group design pattern. The experimental animals used in this study were 32 male Wistar rats, physically healthy, 2-3 months old, with body weight between 200-250 grams. The sample size was determined by the Federer formula, namely: (t - 1) (r - 1) ≥ 15, and the minimum sample size for each treatment was 16 rats. The results showed a significant relationship between the number of fibroblast tissue per visual field in Wistar rats after tooth extraction with the administration of Turmeric Extract (Curcuma Longa) 50% concentration and Turmeric Extract (Curcuma Longa) 100% concentration, p=0.008 (p<0.05). In conclusion, turmeric extract (Curcuma longa) 50% and 100% are effective in accelerating wound healing time after tooth extraction of Wistar rats. Turmeric extract (Curcuma longa) 100% is more effective than turmeric extract (Curcuma longa) 50% in accelerating wound healing time after tooth extraction of Wistar rats because the flavonoid content in turmeric extract (Curcuma longa) 100% which helps accelerate wound healing is higher than turmeric extract (Curcuma longa) 50%.
Keywords: Curcuma longa Linn, Wound healing, Tooth Extraction.
Title: Effectiveness Test of Turmeric Ethanol Extract (Curcuma Longa) in Accelerating Wound Healing after Tooth Extraction in Wistar Rats
Author: Gao Yanshi
International Journal of Interdisciplinary Research and Innovations
ISSN 2348-1218 (print), ISSN 2348-1226 (online)
Vol. 11, Issue 1, January 2023 - March 2023
Page No: 73-79
Research Publish Journals
Website: www.researchpublish.com
Published Date: 27-March-2023
