Abstract: Typhoid fever is a disease caused by infection with Salmonella typhi bacteria which is transmitted through consumption of contaminated food or water. WHO announces typhoid fever patients around the world to reach 17 million every year. Infection is one of the biggest causes of death in Indonesia. From these data, the government needs to take action to improve public health. However, a healthy world launches interventions in the implementation of curative therapy for typhoid fever, one of which is Salmonella typhi (MDRST). One alternative is to use active substances contained in medicinal plants. The general objective of this study was to study the inhibitory test results of extract of Bali robusta coffee beans (Coffea canephora) against Salmonella typhi in vitro. This type of research is experimental with post-test only. The Group Control design used the diffusion disk method (Kirby-bauer) with a sample size of 30 samples. The conservation group was given Robusta coffee bean extract with a concentration of 25%, 50%, 75%. Then the positive control was given ceftriaxone, and 96% ethanol in the disk is blank as a negative control. The results of the study were formed by inhibition zones at a concentration of 25% by 6.33 mm, a concentration of 50% by 8.5 mm, and a concentration of 75% by 10.5 mm. This study could show that Bali Robusta coffee extract could inhibit the growth of S. typhi in vitro with the results of the analysis associated with differences (p <0.05) between Bali Robusta coffee extract at concentrations of 25%, 50%, and 75% Salmonella typhi in vitro. The concentration of 75% becomes the most effective concentration in inhibiting the growth of Salmonella typhi.
Keywords: Bali Robusta Coffee extract, inhibitory test, Salmonella typhi.
Title: EFFECTS OF ANTIBACTERIAL SUBSTANCE OF BALI ROBUSTA COFFEE (Coffea canephora) SEED TOWARD Salmonella typhi GROWTH
Author: Muhammad Fakhri Barustan, Made Agus Hendrayana, Komang Januartha Putra Pinatih, I Dewa Made Sukrama
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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