Abstract: The study was designed to assess the Hypolipidaemic and Hypoglycaemic function of watermelon seed extracts in Streptozocin induced Diabetic Albino rats. Total of twenty rats were randomly allocated into three (3) groups of five (5) rats each; Non Diabetic Control, Diabetic Control and the Diabetes treated with 200mg of watermelon seed extracts for a period of 28 days. Diabetes was induced by single intraperitonial injection of Streptozocin (60mg/kg b.w). After 28th treatment, the rats were sacrificed under Diethyl ether anaesthesia and the blood was collected directly from heart. Serum concentration of glucose, Cholesterol, Triglycerides, HDL and LDL of all the animals in each group were determined. The results shows a significant reduction (p<0.05) of Fasting glucose, cholesterol, TG and LDL cholesterol of Diabetic treated with 200mg concentration of seed extracts when compared with Normal and Diabetic Controls. In Conclusion, watermelon seed extract therefore exhibits both Hypolipidaemic and Hypoglycaemic property.
Keywords: Diabetes mellitus, Lipid Profile, Watermelon seed extracts, Fasting Blood sugar.
Title: Effects of Watermelon Seed Extracts on Fasting Lipid Profile in Streptozocin Induced Diabetic Albino Rats
Author: Muhammad, Y., Saidu, A.Y., Muazu, S., Wali, U., Yeldu, M.H., Abubakar N, Umar, F.A, A, Muhammad, Bako, H
International Journal of Interdisciplinary Research and Innovations
ISSN 2348-1218 (print), ISSN 2348-1226 (online)
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