Abstract: The analysis of semen has been used to diagnose complications associated with reproductive health. It is also worth noting how the same diagnostic procedure is accurate in determining fertility as well as embryo development. The objective of this systematic review was to assess the role of sperm chromatin and sperm maturity to fertility and embryo development. The study included 28 articles from the PROQUEST online database. Several inclusion criteria were used in the selection of relevant articles. The criteria were: (1) the year of publishing, where studies published in 2000 or later were included, (2) studies that applied primary data, and (3) the relevance of the articles as per the independent and dependent variables. The results showed that sperm chromatin and sperm maturity play critical roles in male fertility and embryo development. Regarding the former, the researchers agreed that sperm chromatin plays a major role in the transmission of genetic information. Therefore, the resulting genetic makeup of the embryo depends on the normality or abnormalities of the sperm chromatin. Concerning the latter, this review confirmed a high level of agreement among scholars that a mature spermatozoa is more likely to fertilize than an immature one. The practical implication of this study is the justification of fertility diagnostic tests that examine the sperm chromatin structure and functionality.
Keywords: Reproductive health, Spermatozoa, Chromatin, Fertility, Embryo development.
Title: The Role of Sperm Chromatin Compactness and Sperm Maturity to Fertility and Embryo Development
Author: Eko Budi Siswidiyanto, Eni Maria Sisca, Ria Margiana, Jefry Albari Tribowo, Pety Narulita, Zakiyatul Faizah
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 10, Issue 1, April 2022 - September 2022
Page No: 8-14
Research Publish Journals
Website: www.researchpublish.com
Published date: 12-April-2022
