Abstract: The aim of this study was to investigate the effect of ethanolic extract and juice of Chrysophyllum albidum fruit on hormonal and spermatogenic indices of male wistar rats as proviron served as a reference standard. Twenty- four male wistar rats (150-190 g) were randomly distributed into four groups of six rats each. Group 1 served as control; group 2 received ethanolic extract of Chrysophyllum albidum fruit (ECAF) [100 mg/kg orally (p.o)]; groups 3 received juice of Chrysophyllum albidum fruit (JCAF) [100 mg/kg p.o] and groups 4 received proviron (PRV) [25mg/kg p.o]. Administration of ECAF and JCAF significantly (p<0.05) elevated the serum Testosterone, FSH, LH by 40%, 57% and 51% respectively and lower prolactin by 65% for ECAF and 32.3%, 40.3% and 29% respectively and Prolactin lowered by 31.3% for JCAF relative to the control. In addition, administration of ECAF and JCAF significantly (p<0.05) elevated Sperm Motility, Volume and Count by 40.3%, 60% and d35% respectively for ECAF and 30%, 25% and 38% respectively for JCAF. Conclusions: ECAF and JCA improved hormonal and spermatogenic indices of male wistar rats but ECAF is a more efficient intervention in ethnomedicine against infertility and male erectile dysfunction.
Keywords: Chrysophyllum albidum, hormonal indices, spermatogenic indices, proviron, ethnomedicine.
Title: Ethanolic Extract and Juice of Chrysophyllum albidum Fruit Improve Hormonal and Spermatogenic Indices of Male Wistar Rats
Author: Semiu Lawal, Roshidat Tijani, Kayode Koleoso, Ahmed Fasasi
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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