Abstract: Serum 25-hydroxyvitamin D3 [25(OH)D3] concentrations are currently recognized as the functional status indicator for vitamin D. Evidence is reviewed that shows that serum 25(OH)D3 concentrations of < 80 nmol/L are associated with reduced calcium absorption, osteoporosis, and increased fracture risk. For typical older individuals, supplemental oral intakes of ~1300 IU/d are required to reach the lower end of the optimal range. Evidence of substantial problems in routine clinical measurement of serum 25(OH)D3 concentrations among patients is cited. There is great need for standardization and improved reproducibility and sensitivity of measurements of serum 25(OH)D3 concentrations.
Keywords: Rickets, osteomalacia, osteoporosis, calcium absorption, fractures, serum 25-hydroxyvitamin D3.
Title: Functional indices of vitamin D status and consequences of vitamin D deficiency
Author: FAHAD ABDULAZIZ ALKHARAAN, NAWAF TURKY ALENIZI, MOHAMMED HADI ALHABABI, NORA MUNAHI ALMUTAIRI, Abdullah Abdulrzaq Aljuwayi
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
Vol. 10, Issue 4, October 2022 - December 2022
Page No: 92-96
Research Publish Journals
Website: www.researchpublish.com
Published Date: 28-December-2022
