Abstract: Coronary Heart Disease (CHD) is the number one cause of death in the current world. Since numerous reasons heighten the risk of CHD, this review will focus only on genetic risk factors. Known for its ability to analyze and enhance chromosome mapping by garnering tons of human tests by its agnostic approach, conducting Genome-Wide Association Studies (GWAS) to examine genetic patterns in patients has perceived many undiscovered hidden genes. For instance, Sortilin is a gene vitally linked to cardiovascular diseases (CVD) risks and plasma LDL cholesterol levels. Moreover, GWAS could predict CVD risk furthermore and is beneficial for personalized medical treatment. Applying the understanding of genetics could create biomarkers that detect early stages of disease development and provide a precise diagnosis. Precise risk assessments and individualized treatment benefit projections are necessary. Accurate risk ratings, more potent drugs, and specialized evaluation of treatment are three tools to improve traditional risk estimation of CVD.
Keywords: Coronary Heart Disease; Genome-Wide Association Studies (GWAS); SORT1
Title: Genetic Risks of Cardiovascular Diseases
Author: Wachirawit Angkatavanich
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 10, Issue 1, April 2022 - September 2022
Page No: 161-167
Research Publish Journals
Website: www.researchpublish.com
Published Date: 23-July-2022
