Abstract: Amaranthus Gangeticus is a medicinal plant. Our aim is to investigate its organ protection property. Hence ethanolic extract of Amaranthus Gangeticus leaves (AG) was taken and the parameters studied were SGPT, SGOT, total bilirubin, direct bilirubin, total cholesterol, HDL and ALP activities. Results of bio-chemical studies of blood samples of Paracetamol treated animals showed significant increase in the levels of serum markers and decrease in HDL level reflecting the liver injury caused by Paracetamol. Whereas, the animals treated with ethanolic extract of AG showed significant dose dependent decrease in the elevated levels of serum markers and increase in HDL levels indicating the protection of hepatic cells. Therefore these results concluded that, the ethanolic extract afford significant protection against Paracetamol induced hepatocellular injury and remarkable rejuvenation of these tissues found in histopathological studies which may be attributed due to polyphenols and antioxidant in it.
Keywords: Ethanolic extract of Amaranthus Gangeticus leaves and serum markers.
Title: Hepatoprotective activities of Amaranthus gangeticus leaves against paracetamol induced hepatic damage in albino rats
Author: G. Jyoti Jain, S. Ramachandra Setty
International Journal of Life Sciences Research
ISSN 2348-313X (Print), ISSN 2348-3148 (online)
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