Abstract: Molluscum contagiosum (MC) is a mucocutaneous disorder of the poxviridae family with a wide range of atypical presentation in patients with impaired cellular immunity. Objectives: To determine the prevalence of Molluscum contagiosum amongst HIV/AIDS patients who were seen at the Aids Preventive Initiative in Nigeria (APIN) clinic in Jos University Teaching Hospital (JUTH) Jos, Plateau State, Nigeria. Materials and methods: A one year retrospective review of histopathological cases of molluscum contagiosum amongst HIV patients diagnosed at the department of pathology Jos University Teaching Hospital(JUTH), Jos. Archival records and paraffin embedded tissue blocks were retrieved, resectioned and stained. Results are presented as Tables and charts. Results: Overall, fifteen (15) cases of molluscum contagiosum were histologically diagnose within the review period. This account for 10% of all skin manifestation related to HIV diagnose in the department. Of the 15 cases 6 (40%) were males and 9 (60%) were females given a male to female ratio of 0.7:1. The age range of patients were from 21-50 years, commonest anatomical site was the face followed by the trunk.
(60%) of the cases presented with CD4 lymphocyte count below 200 cell/ml while 6(40%) presented with a CD4+lymphocyte count between 200 to 500 cells/ml. Similarly, more than half of the cases are seen in patients with viral load of over 100,000 copies/ml, while the rest have viral load of 10,000-100,000 copies/ml. All patients were on various stages of highly active antiretroviral therapy (HAART). Conclusion: The study demonstrated that molluscum contagiosum is an atypical presentation in patients with HIV/AIDS with inverse relationship with CD4+lymphocytes counts and viral load.
Keywords: HIV/AIDS, Molluscum contagiosum, Jos, North Central Nigeria.
Title: HISTOPATHOLOGIC REVIEW OF HIV/AIDS ASSOCIATED MOLLUSCUM CONTAGIOSUM IN JOS NORTH CENTRAL NIGERIA
Author: J A.Ngbea, P.O. Echekwube R.A. Vhriterhire, U.L Ervihi, TJ. Igbudu, A.Onyemocho, B.M. Mandong
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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