Abstract: We aim in this study to review the current evidence pertaining to the efficacy of the hyperbaric oxygen (HBO) therapy in the treatment of children with epilepsy and to report adverse events.
Methodology: We conducted a descriptive systematic review using the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines for all clinical trials concerning the use of HBO for the treatment of epilepsy attacks in children aged from birth-21 years. Primary outcome assesses the effects of HBO therapy for the treatment of epilepsy. Secondary outcome measures evaluated any reported adverse events of HBO therapy.
Results: Thirty-one abstracts were identified out of which 22 were excluded and one was a duplicate. Eight full text articles were included in this study with three retrospective analyses, three case reports, one non-blinded randomized clinical trial, and one was a prospective observational study.
Conclusion: No study has evaluated the effect of HBO therapy on epilepsy in children. With the rare complication of oxygen toxicity seizures, HBO therapy may complicate epilepsy. However, new evidence showing that seizures not secondary to oxygen toxicity could be safely relieved by HBO therapy. Further randomized clinical trials assessing the effect of HBO therapy in children and adolescents with epilepsy is recommended.
Keywords: HBO Therapy (Hyperbaric Oxygen), Evidence Pertaining.
Title: Hyperbaric Oxygen Therapy in Children with Epilepsy: A Review of the Evidence
Author: Al Soqih, Norah S
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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