In-vitro and in-vivo studies of excipient package compatibilities and functionality in transiting an undamaged stratum corneum

David Richard

Abstract: The basic science technology of Dynamic Infusion TechnologyTM is demonstrated and the efficacy of a new transdermal delivery technology is evaluated in-vivo and in-vitro. Dynamic Infusion Technology has the ability to transport topically applied constituents to the intact epidermis without predicate damage to the stratum corneum. The product line includes a series of easily applied lotions and creams. The proprietary delivery system was developed from the company’s previous research and product development in liposome and vesicle delivery of active ingredients. The transit of a large molecule, hyaluronic acid (HA), as well as additional active molecules such as argireline, beta glucan, tocopheryl acetate, ascorbyl palmitate, and niacinimide into the skin was demonstrated without the use of a treatment modality. The proprietary formulation of vesicles within the host serums, lotions, and creams allow the transit of HA into the skin, which helps with collagen remodeling and skin plumping.

Keywords: Transit, Delivery, Formulation, Polymers, Skin Barrier.

Title: In-vitro and in-vivo studies of excipient package compatibilities and functionality in transiting an undamaged stratum corneum

Author: David Richard

International Journal of Healthcare Sciences

ISSN 2348-5728 (Online)

Research Publish Journals

Vol. 6, Issue 2, October 2018 – March 2019

Citation
Share : Facebook Twitter Linked In

Citation
In-vitro and in-vivo studies of excipient package compatibilities and functionality in transiting an undamaged stratum corneum by David Richard