Abstract: The critical phase of dengue fever is characterized by severe plasma leakage leading to severe shock. Colloids are indicated in severe dengue with profound shock. In this study, we retrospectively analyzed the physiological status at admission, indications, and adverse effect of colloid in patients with severe dengue over the period of last 4 years. Of 3039 patients with dengue fever admitted to our hospital, there were a total of 143 patients with severe dengue. The compensated shock was the common presentation (n=117) and 26 children presented with hypotensive shock.All patients with severe dengue required colloid therapy( synthetic in 126, natural in 3, both in 14). Though 92% of patients had coagulopathy, clinical bleeding was observed in 1/5th of them and Disseminated Intravascular Coagulopathy(DIC) in 6% of patients. Refractory shock, DIC, Multiorgan Dysfunction Syndrome, Fulminant Hepatic Failure either alone or in combination were the causes of death in 9 children presenting with shock to the Emergency Department(ED).
Keywords: Severe Dengue, Shock, Colloid.
Title: INDICATIONS AND ADVERSE EFFECTS OF COLLOIDS AND OUTCOME IN CHILDREN WITH DENGUE FEVER
Author: Lakshmi Muthukrishnan, Radhika Raman
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
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