Intestinal Microbiota Transplantation (IMT) For Recurrent Clostridium Difficile Infection (CDI)

Sharifah Radhi Alsammak, Fatimah Abdullah Al Zaher, Basmah Baqer Ali Alshammasi, Noor Baqer Ali Alshamase, Zahra Zaki Al Zahir

Abstract: Clostridium difficile infection (CDI) is a intestinal disease believed to be causally related to perturbations to the intestinal microbiota. The term microbaiota describes the neighborhood of bacteria that live in a specific area of the body. This overview aimed to discuss and highlight the most recent evidence about intestinal microbiota transplantation for recurrent Clostridium difficile infection, through systematically reviewing articles concerning the same topic. We performed an electronic search through Medline, and Embase databases (up to November 2016) for publications, we limited our search to English language Articles, and to every study discussing Fecal bacteriotherapy, which is also called intestinal microbiota transplantation (IMT) as treatment for recurrent Clostridium difficile infection. The role of IMT has actually come a long way from its start in transfaunation, and we are simply in the dawn of realizing its full potential to treat a range of gastrointestinal disorders. Most promising is its function in CDI, which has become a life-threatening and financially crippling epidemic in healthcare worldwide. With a much better understanding of the complexities of the colonic microbiome and its role in colonic pathophysiology, IMT has the potential to become the requirement of take care of CDI treatment, and might be the potential answer to other intestinal conditions in years to come. Keywords: CDI treatment, intestinal microbiota transplantation (IMT), Embase databases. Title: Intestinal Microbiota Transplantation (IMT) For Recurrent Clostridium Difficile Infection (CDI) Author: Sharifah Radhi Alsammak, Fatimah Abdullah Al Zaher, Basmah Baqer Ali Alshammasi, Noor Baqer Ali Alshamase, Zahra Zaki Al Zahir International Journal of Healthcare Sciences ISSN 2348-5728 (Online) Research Publish Journals

Vol. 4, Issue 2, October 2016 – March 2017

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Intestinal Microbiota Transplantation (IMT) For Recurrent Clostridium Difficile Infection (CDI) by Sharifah Radhi Alsammak, Fatimah Abdullah Al Zaher, Basmah Baqer Ali Alshammasi, Noor Baqer Ali Alshamase, Zahra Zaki Al Zahir