Abstract: Laboratory parameters are used to monitor diseases and treatment processes. Abnormalities in laboratory parameters of HIV patients before commencement of anti-retroviral therapy and their association with patients’ treatment outcomes were evaluated. Patients were followed up and data on laboratory investigations and WHO clinical staging of were collected from 330 patients in 2021 and 2022. One hundred and thirty-six (41.2%) were found to be anaemic. Mean baseline CD4 count was 389.9 ± 293.7. The majority had other baseline laboratory parameters within normal range, creatinine 308 (93.3%), ALAT 285 (86.4%) and ASAT 253 (76.7%). Predictor of WHO stage 1 at 6 months was CD4 ≥ 350 cells/mm3, OR 1.474 (95% CI 0.096 – 0.545). Predictor of viral suppression at 6 months was also CD4 ≥ 350 cells/mm3, OR 0.994 (95% CI 0.217 – 0.632).
Keywords: ALAT, ASAT, CD4, creatinine, HAART, HIV, WHO staging, viral suppression.
Title: LABORATORY PARAMETERS ABNORMALITIES IN HIV PATIENTS AND THEIR ASSOCIATION WITH PATIENTS’ OUTCOME IN A TERTIARY CARE CENTRE IN SOUTH EAST NIGERIA
Author: Chinyerem Cynthia Nwachukwu, Gabriel Ifeanyi Eyisi, Ifeoma Anne Njelita, Chijioke Amara Ezenyeaku, Amaechi Chinedu Nwachukwu, Obioma Okechi
International Journal of Healthcare Sciences
ISSN 2348-5728 (Online)
Vol. 10, Issue 2, October 2022 - March 2023
Page No: 213-220
Research Publish Journals
Website: www.researchpublish.com
Published Date: 10-February-2023
